HitPredict

Interactor 1: H2A1B (P04908)
Histone H2A type 1-B/E (Histone H2A.2) (Histone H2A/a) (Histone H2A/m)
Gene: H2AC4

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	12665567
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HAT_KAT11~Histone
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 130 Hs			1 2442
+	Mm
		101453 H2A3_MOUSE (1-130): 3.34e-68: 203: 99.23		F8VPR5_MOUSE (1-2442): 0: 1077: 95.67
+	Hs
		391671 H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		998866 H2A2B_HUMAN (1-130): 8.97e-67: 199: 93.85		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Mm
		70932 H2A3_MOUSE (1-130): 3.34e-68: 203: 99.23		EP300_MOUSE (1-2426): 0: 867: 53.61
+	Hs
		998781 H2A2C_HUMAN (1-130): 1.54e-65: 196: 95.39		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		555430 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		1087066 H2A2C_HUMAN (1-130): 1.54e-65: 196: 95.39		PHIP_HUMAN (1045-1205): 3.22e-45: 183: 30.36
+	Hs
		1067005 H2A2A_HUMAN (1-130): 2.9e-68: 203: 96.92		BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89
+	Hs
		391554 H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00		BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53
+	Hs
		1067038 H2A2B_HUMAN (1-130): 8.97e-67: 199: 93.85		BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89
+	Hs
		631492 H2A2B_HUMAN (1-130): 8.97e-67: 199: 93.85		BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53
+	Hs
		1066979 H2A2C_HUMAN (1-130): 1.54e-65: 196: 95.39		BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89
+	Hs
		555299 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53
+	Hs
		555470 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89
+	Hs
		554260 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		MUC1_HUMAN (1947-2441): 7.35e-18: 93.3: 11.02
+	Hs
		391768 H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Hs
		1087035 H2A2C_HUMAN (1-130): 1.54e-65: 196: 95.39		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Hs
		391802 H2A1B_HUMAN (1-130): 4.35e-68: 202: 100.00		KMT2C_HUMAN (1945-2437): 8.84e-10: 67.1: 13.89
+	Hs
		555528 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		PB1_HUMAN (1040-1275): 1.29e-12: 76: 14.83
+	Hs
		555434 H2AX_HUMAN (1-130): 3.67e-64: 193: 88.06		BPTF_HUMAN (1831-2314): 7.5e-12: 73.6: 11.09