Protein: HYD
E3 ubiquitin-protein ligase hyd (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase hyd) (Protein hyperplastic discs)

Gene: HYD
Organism: Drosophila melanogaster
Interactions: 23
UniProt ID: P51592

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0007112 - male meiosis cytokinesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

613934

SGG
Protein kinase shaggy

2

8

Small-scale

0.571

High

904451

Q7KMQ0
26S proteasome regulatory subunit 7

2

15

High-throughput

0.521

High

904450

SEM1A
Semaphorin-1A

1

2

High-throughput

0.489

High

384761

HSP22
Heat shock protein 22

1

6

High-throughput

0.479

High

391823

HSP71
Major heat shock 70 kDa protein Ab

1

8

High-throughput

0.479

High

624292

CI
Transcriptional activator cubitus interruptus

1

12

Small-scale

0.479

High

904457

AKIRN
Akirin

1

1

Small-scale

0.479

High

904460

MYC
Myc proto-oncogene protein

1

13

High-throughput

0.479

High

669584

OSKA
Maternal effect protein oskar

1

0

Small-scale

0.458

High

384980

HSP27
Heat shock protein 27

1

6

High-throughput

0.445

High

437979

PYR1
Multifunctional protein r

1

11

High-throughput

0.445

High

904448

HSP70
Major heat shock 70 kDa protein Aa

1

8

High-throughput

0.445

High

904449

Q0E8S4
Semaphorin-1A

1

1

High-throughput

0.442

High

119568

M9PAY7
Pi3K21B, isoform C

1

17

High-throughput

0.437

High

2199

A0A0B4JD40
RING-type E3 ubiquitin transferase

1

0

High-throughput

0.426

High

571051

REF2P
Protein ref(2)P

1

0

High-throughput

0.426

High

904452

Q8IPU8
BNIP3, isoform B

1

0

High-throughput

0.426

High

904454

Q9VGN4
Sarcomere length short, isoform B

1

11

High-throughput

0.407

High

904456

Q9VM97
Thrombospondin, isoform A

1

11

High-throughput

0.407

High

904458

Q9W0L7
ubiquitinyl hydrolase 1

1

11

High-throughput

0.407

High

904453

Q95RF6
LD34461p

1

0

High-throughput

0.249

Low

904455

ZUC
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.249

Low

904459

Q9W4C1
IP13321p

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025