HitPredict

Interactor 1: H2A1 (P04911)
Histone H2A.1
Gene: HTA1

Interactor 2: ORC1 (P54784)
Origin recognition complex subunit 1 (Origin recognition complex 120 kDa subunit)
Gene: ORC1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.799

Property	Details
Experiments	31263106, 20595233
Identification Methods	x-ray crystallography, pull down, affinity chromatography technology
Interaction Type	association, direct interaction, physical association

Property	Details
Interacting Pfam domains	BAH~Histone
Common GO terms	GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 132 Sc			1 914
+	Sc
		392528 H2A2_YEAST (1-132): 4.09e-62: 187: 98.49		ORC1_YEAST (1-914): 0: 798: 100.00
+	Sc
		392015 H2A1_YEAST (1-132): 2.22e-62: 188: 100.00		SIR3_YEAST (1-914): 0: 587: 26.50
+	Sc
		392240 H2A2_YEAST (1-132): 4.09e-62: 187: 98.49		SIR3_YEAST (1-914): 0: 587: 26.50
+	Hs
		1033386 H2A2C_HUMAN (3-130): 2.4e-62: 188: 73.44		ORC1_HUMAN (155-908): 9.77e-118: 381: 21.21
+	Sc
		392530 H2A2_YEAST (1-132): 4.09e-62: 187: 98.49		ORC4_YEAST (385-711): 1.69e-45: 174: 13.51
+	Hs
		875272 H2AJ_HUMAN (3-130): 7.26e-63: 189: 73.44		TERA_HUMAN (420-667): 3.72e-25: 114: 10.00
+	Hs
		555371 H2AX_HUMAN (3-129): 1.71e-61: 186: 73.23		TERA_HUMAN (420-667): 3.72e-25: 114: 10.00
+	Hs
		391577 H2A1B_HUMAN (3-129): 1.67e-62: 189: 74.02		RFC1_HUMAN (147-633): 9.78e-20: 97.4: 12.66