HitPredict

Interactor 1: H2A2 (P04912)
Histone H2A.2
Gene: HTA2

Interactor 2: RSC2 (Q06488)
Chromatin structure-remodeling complex subunit RSC2 (RSC complex subunit RSC2) (Remodel the structure of chromatin complex subunit 2)
Gene: RSC2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.80	0.731

Property	Details
Experiments	19106085, 37968396, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BAH~Histone
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 132 Sc			1 889
+	Hs
		1067038 H2A2B_HUMAN (3-127): 3.9e-63: 190: 74.40		BRD3_HUMAN (7-385): 2.06e-68: 243: 15.92
+	Hs
		1066979 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		BRD3_HUMAN (7-385): 2.06e-68: 243: 15.92
+	Hs
		998866 H2A2B_HUMAN (3-127): 3.9e-63: 190: 74.40		EP300_HUMAN (4-191): 1.16e-32: 139: 18.75
+	Hs
		998781 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		EP300_HUMAN (4-191): 1.16e-32: 139: 18.75
+	Hs
		631492 H2A2B_HUMAN (3-127): 3.9e-63: 190: 74.40		BRD2_HUMAN (2-255): 2.31e-29: 127: 15.89
+	Hs
		391554 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		BRD2_HUMAN (2-255): 2.31e-29: 127: 15.89
+	Hs
		244848 H2A1J_HUMAN (3-128): 1.79e-63: 191: 74.60		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Hs
		244634 H2A2B_HUMAN (3-127): 3.9e-63: 190: 74.40		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Hs
		244795 H2A1H_HUMAN (3-128): 3.42e-63: 190: 75.40		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Hs
		243783 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Hs
		1300654 H2A1A_HUMAN (3-130): 1.25e-64: 194: 74.22		BRD7_HUMAN (2-258): 1.02e-24: 112: 12.36
+	Sc
		392293 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		SNF2_YEAST (8-168): 6.81e-25: 114: 23.93
+	Hs
		1296215 H2A1H_HUMAN (3-128): 3.42e-63: 190: 75.40		BRD7_HUMAN (2-258): 1.02e-24: 112: 12.36
+	Hs
		1087066 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		PHIP_HUMAN (19-293): 6.82e-20: 97.9: 12.77
+	Hs
		1087035 H2A2C_HUMAN (3-130): 9.18e-63: 189: 73.44		PB1_HUMAN (234-742): 1.78e-19: 96.7: 14.64
+	Sc
		392389 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		BDF1_YEAST (26-219): 5.23e-19: 94.4: 12.63
+	Sc
		392382 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		SPT7_YEAST (158-404): 1.37e-18: 93.5: 11.86
+	Sc
		392513 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		RSC1_YEAST (4-149): 1.8e-12: 73.6: 18.24
+	Sc
		392357 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		STH1_YEAST (275-377): 2.49e-11: 69.8: 24.27
+	Sc
		392537 H2A2_YEAST (1-132): 1.1e-62: 189: 100.00		RSC4_YEAST (34-128): 1.91e-10: 66.7: 27.84