HitPredict

Interactor 1: ITB2 (P05107)
Integrin beta-2 (Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD antigen CD18)
Gene: ITGB2

Interactor 2: ICAM1 (P05362)
Intercellular adhesion molecule 1 (ICAM-1) (Major group rhinovirus receptor) (CD antigen CD54)
Gene: ICAM1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.710

The method score is based on:

Property	Details
Experiments	10352278, 11279101, 7642561, 20187292, 12208882
Identification Methods	pull down, enzyme linked immunosorbent assay
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005178 - integrin binding GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0007155 - cell adhesion GO:0007159 - leukocyte cell-cell adhesion and 5 others more... GO:0009897 - external side of plasma membrane GO:0009986 - cell surface GO:0016020 - membrane GO:0033627 - cell adhesion mediated by integrin GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	769
Hs

1	532

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024