HitPredict

Interactor 1: S10A8 (P05109)
Protein S100-A8 (Calgranulin-A) (Calprotectin L1L subunit) (Cystic fibrosis antigen) (CFAG) (Leukocyte L1 complex light chain) (Migration inhibitory factor-related protein 8) (MRP-8) (p8) (S100 calcium-binding protein A8) (Urinary stone protein band A)
Gene: S100A8

Interactor 2: PINK1 (Q9BXM7)
Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Gene: PINK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	31300519, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005856 - cytoskeleton
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 93 Hs			1 581
+	Hs
		661423 S10A2_HUMAN (1-92): 1.72e-29: 102: 26.04		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		1125344 FILA2_HUMAN (2-89): 4.61e-25: 99.1: 29.35		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		416508 S10A9_HUMAN (2-88): 5.5e-28: 99.1: 26.09		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		596315 FILA_HUMAN (2-90): 4.67e-19: 81.8: 27.96		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		1197657 S1A7A_HUMAN (3-91): 1.56e-17: 72.5: 24.21		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		682050 CRNN_HUMAN (2-91): 1.35e-27: 105: 34.04		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	Hs
		707403 S10A3_HUMAN (1-90): 1.52e-28: 100: 22.34		AKT3_HUMAN (110-573): 2.43e-120: 365: 13.88
+	Hs
		681685 S10A3_HUMAN (1-90): 1.52e-28: 100: 22.34		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	Hs
		784037 S1A7A_HUMAN (3-91): 1.56e-17: 72.5: 24.21		KPCI_HUMAN (56-568): 6.26e-123: 376: 13.92
+	Hs
		682028 S10AE_HUMAN (3-80): 1.13e-20: 80.2: 20.25		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	Hs
		380732 S100B_HUMAN (2-89): 3.95e-27: 96.4: 32.61		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89
+	Hs
		615217 S10A1_HUMAN (1-90): 8.66e-33: 110: 36.17		KS6A1_HUMAN (157-555): 9.95e-91: 296: 15.63
+	Hs
		642947 S10A4_HUMAN (1-93): 4.07e-31: 106: 27.84		KS6A1_HUMAN (157-555): 9.95e-91: 296: 15.63
+	Hs
		638962 S100P_HUMAN (2-92): 1.25e-30: 105: 35.79		KS6A1_HUMAN (157-555): 9.95e-91: 296: 15.63
+	Hs
		661265 S10A2_HUMAN (1-92): 1.72e-29: 102: 26.04		KS6A1_HUMAN (157-555): 9.95e-91: 296: 15.63
+	Hs
		380782 S100B_HUMAN (2-89): 3.95e-27: 96.4: 32.61		KS6A1_HUMAN (157-555): 9.95e-91: 296: 15.63
+	Hs
		416623 S10A6_HUMAN (1-88): 9.59e-27: 95.3: 24.44		KS6A1_HUMAN (157-555): 9.95e-91: 296: 15.63
+	Hs
		380882 S100B_HUMAN (2-89): 3.95e-27: 96.4: 32.61		KCC2A_HUMAN (221-538): 5.11e-82: 266: 20.62