HitPredict

Interactor 1: S10A8 (P05109)
Protein S100-A8 (Calgranulin-A) (Calprotectin L1L subunit) (Cystic fibrosis antigen) (CFAG) (Leukocyte L1 complex light chain) (Migration inhibitory factor-related protein 8) (MRP-8) (p8) (S100 calcium-binding protein A8) (Urinary stone protein band A)
Gene: S100A8

Interactor 2: CYLD (Q9NQC7)
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)
Gene: CYLD

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27591049
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008270 - zinc ion binding GO:0045087 - innate immune response
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 93 Hs			1 956
+	Hs
		1206200 HORN_HUMAN (2-89): 7.34e-30: 112: 25.00		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1125351 FILA2_HUMAN (2-89): 4.61e-25: 99.1: 29.35		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		416518 S10A9_HUMAN (2-88): 5.5e-28: 99.1: 26.09		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		596325 FILA_HUMAN (2-90): 4.67e-19: 81.8: 27.96		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1336556 S10AE_HUMAN (3-80): 1.13e-20: 80.2: 20.25		CYLD_HUMAN (1-956): 0: 1872: 100.00