Interactor 1: PAI1 (P05121)
Plasminogen activator inhibitor 1 (PAI) (PAI-1) (Endothelial plasminogen activator inhibitor) (Serpin E1)
Gene: SERPINE1

Interactor 2: PAI1 (P05121)
Plasminogen activator inhibitor 1 (PAI) (PAI-1) (Endothelial plasminogen activator inhibitor) (Serpin E1)
Gene: SERPINE1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 10731421
Identification Methods x-ray crystallography
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains Serpin~Serpin
Common GO terms GO:0001525 - angiogenesis
GO:0002020 - protease binding
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region
and 33 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 402
Hs

1 402
+ Hs
+ Hs
+ Hs
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024