HitPredict

Interactor 1: KPCG (P05129)
Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)
Gene: PRKCG

Interactor 2: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36931259
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	14-3-3~C1_1
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 697 Hs			1 248
+	Hs
		397155 KPCG_HUMAN (1-697): 0: 772: 100.00		1433E_HUMAN (2-246): 4.41e-146: 410: 60.41
+	Hs
		566348 KPCA_HUMAN (1-683): 0: 725: 70.03		1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37
+	Hs
		397154 KPCG_HUMAN (1-697): 0: 772: 100.00		1433G_HUMAN (1-242): 1.86e-98: 289: 65.16
+	Hs
		566293 KPCA_HUMAN (1-683): 0: 725: 70.03		1433T_HUMAN (1-238): 9.98e-108: 312: 71.85
+	Hs
		566346 KPCA_HUMAN (1-683): 0: 725: 70.03		1433G_HUMAN (1-242): 1.86e-98: 289: 65.16
+	Hs
		408587 KPCB_HUMAN (1-681): 0: 716: 67.79		1433G_HUMAN (1-242): 1.86e-98: 289: 65.16
+	Hs
		681682 AKT1_HUMAN (215-677): 1.23e-151: 450: 33.68		1433S_HUMAN (1-248): 3.48e-158: 440: 100.00
+	Hs
		909585 KPCD1_HUMAN (24-669): 6.8e-150: 460: 18.39		1433E_HUMAN (2-246): 4.41e-146: 410: 60.41
+	Hs
		681770 AKT1_HUMAN (215-677): 1.23e-151: 450: 33.68		1433E_HUMAN (2-246): 4.41e-146: 410: 60.41
+	Hs
		927067 KPCD1_HUMAN (24-669): 6.8e-150: 460: 18.39		1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37
+	Hs
		681776 AKT1_HUMAN (215-677): 1.23e-151: 450: 33.68		1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37
+	Hs
		646908 KPCD1_HUMAN (24-669): 6.8e-150: 460: 18.39		1433T_HUMAN (1-238): 9.98e-108: 312: 71.85
+	Hs
		647354 KS6B2_HUMAN (290-695): 2.01e-149: 444: 36.43		1433T_HUMAN (1-238): 9.98e-108: 312: 71.85
+	Hs
		904582 KPCD1_HUMAN (24-669): 6.8e-150: 460: 18.39		1433G_HUMAN (1-242): 1.86e-98: 289: 65.16
+	Hs
		982031 KPCD1_HUMAN (24-669): 6.8e-150: 460: 18.39		1433F_HUMAN (2-242): 2.78e-96: 283: 64.20
+	Hs
		681766 AKT1_HUMAN (215-677): 1.23e-151: 450: 33.68		1433G_HUMAN (1-242): 1.86e-98: 289: 65.16
+	Hs
		684052 KS6A2_HUMAN (247-664): 7.56e-90: 297: 22.94		1433S_HUMAN (1-248): 3.48e-158: 440: 100.00
+	Dm
		664624 Q94533_DROME (337-695): 4.74e-148: 441: 37.16		1433Z_DROME (1-245): 4.71e-99: 290: 66.12
+	Hs
		982585 KS6B2_HUMAN (290-695): 2.01e-149: 444: 36.43		1433F_HUMAN (2-242): 2.78e-96: 283: 64.20
+	Hs
		909590 KS6A2_HUMAN (247-664): 7.56e-90: 297: 22.94		1433E_HUMAN (2-246): 4.41e-146: 410: 60.41