Protein: PDE9A
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35)

Gene: PDE9A
Organism: Homo sapiens
Interactions: 54
UniProt ID: O76083

Gene Ontology (top 5):
GO:0004114 - 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115 - 3',5'-cyclic-AMP phosphodiesterase activity
GO:0005654 - nucleoplasm
GO:0005783 - endoplasmic reticulum
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

283283

PDE9A
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

3

7

High-throughput

0.874

High

283303

TRI32
E3 ubiquitin-protein ligase TRIM32

8

0

High-throughput

0.726

High

283298

KR108
Keratin-associated protein 10-8

3

9

High-throughput

0.675

High

283306

U119A
Protein unc-119 homolog A

3

1

High-throughput

0.667

High

283285

BAG3
BAG family molecular chaperone regulator 3

3

0

High-throughput

0.646

High

283291

ST1E1
Sulfotransferase 1E1

3

0

High-throughput

0.646

High

283307

LAGE3
EKC/KEOPS complex subunit LAGE3

3

0

High-throughput

0.646

High

283311

CRY2
Cryptochrome-2

3

0

High-throughput

0.646

High

283327

GORS2
Golgi reassembly-stacking protein 2

2

0

High-throughput

0.618

High

283290

CLK1
Dual specificity protein kinase CLK1

3

4

High-throughput

0.616

High

132688

SDCB1
Syntenin-1

2

3

High-throughput

0.606

High

280499

KRT34
Keratin, type I cuticular Ha4

2

1

High-throughput

0.606

High

283289

KRA59
Keratin-associated protein 5-9

2

11

High-throughput

0.606

High

283294

KR122
Keratin-associated protein 12-2

2

9

High-throughput

0.606

High

283295

KR123
Keratin-associated protein 12-3

2

1

High-throughput

0.606

High

283297

KR107
Keratin-associated protein 10-7

2

9

High-throughput

0.606

High

283299

KR109
Keratin-associated protein 10-9

2

10

High-throughput

0.606

High

283300

WDR5
WD repeat-containing protein 5

2

2

High-throughput

0.606

High

283302

KRA11
Keratin-associated protein 1-1

2

9

High-throughput

0.606

High

283316

KRA13
Keratin-associated protein 1-3

2

9

High-throughput

0.606

High

171469

UBD
Ubiquitin D

2

0

High-throughput

0.580

High

283308

IQCB1
IQ calmodulin-binding motif-containing protein 1

2

0

High-throughput

0.580

High

283309

CDC37
Hsp90 co-chaperone Cdc37

2

0

High-throughput

0.580

High

283321

PRP18
Pre-mRNA-splicing factor 18

2

0

High-throughput

0.580

High

283313

NT2NA
Notch homolog 2 N-terminal-like protein A

2

1

High-throughput

0.573

High

283288

RBTN2
Rhombotin-2

1

1

High-throughput

0.573

High

283324

KRA92
Keratin-associated protein 9-2

1

9

High-throughput

0.573

High

283325

KRA42
Keratin-associated protein 4-2

1

9

High-throughput

0.573

High

283322

LSMD1
N-alpha-acetyltransferase 38, NatC auxiliary subunit

1

0

High-throughput

0.549

High

283284

HERC2
E3 ubiquitin-protein ligase HERC2

1

7

High-throughput

0.541

High

283292

FXR1
RNA-binding protein FXR1

1

2

High-throughput

0.541

High

283293

FXR2
RNA-binding protein FXR2

1

2

High-throughput

0.541

High

283315

HIPK1
Homeodomain-interacting protein kinase 1

1

5

High-throughput

0.541

High

283286

ERCC1
DNA excision repair protein ERCC-1

1

0

High-throughput

0.518

High

283287

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.518

High

283296

KR103
Keratin-associated protein 10-3

1

10

High-throughput

0.481

High

67429

NEU1B
E3 ubiquitin-protein ligase NEURL1B

1

2

Small-scale

0.479

High

282377

NEUL1
E3 ubiquitin-protein ligase NEURL1

1

3

Small-scale

0.479

High

283304

TRAF3
TNF receptor-associated factor 3

1

1

Small-scale

0.479

High

283305

KGP2
cGMP-dependent protein kinase 2

1

5

High-throughput

0.479

High

283314

NPHP3
Nephrocystin-3

1

1

High-throughput

0.479

High

283319

RSPRY
RING finger and SPRY domain-containing protein 1

1

3

High-throughput

0.479

High

283301

TFAP4
Transcription factor AP-4

1

0

High-throughput

0.460

High

283326

TRPV6
Transient receptor potential cation channel subfamily V member 6

1

0

High-throughput

0.460

High

283320

PHIPL
Phytanoyl-CoA hydroxylase-interacting protein-like

4

0

High-throughput

0.368

High

66929

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

283310

NFIL3
Nuclear factor interleukin-3-regulated protein

2

0

High-throughput

0.316

High

283312

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

0

High-throughput

0.316

High

283317

CI106
Putative uncharacterized protein encoded by LINC02913

1

0

High-throughput

0.299

High

283323

UTP23
rRNA-processing protein UTP23 homolog

1

0

High-throughput

0.299

High

283328

ZMYM5
Zinc finger MYM-type protein 5

1

0

High-throughput

0.282

High

283329

Q9Y260
ABP/ZF

1

0

High-throughput

0.268

Low

283318

OCC1
Overexpressed in colon carcinoma 1 protein

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024