HitPredict

Interactor 1: KPCG (P05129)
Protein kinase C gamma type (PKC-gamma) (EC 2.7.11.13)
Gene: PRKCG

Interactor 2: DAB2 (P98082)
Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Differentially-expressed protein 2)
Gene: DAB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10542228
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 697 Hs			1 770
+	Hs
		408600 KPCB_HUMAN (1-681): 0: 716: 67.79		DAB2_HUMAN (1-770): 3.91e-90: 301: 100.00
+	Hs
		566327 KPCA_HUMAN (1-683): 0: 725: 70.03		NUMB_HUMAN (22-635): 7.43e-47: 179: 14.20
+	Hs
		408578 KPCB_HUMAN (1-681): 0: 716: 67.79		NUMB_HUMAN (22-635): 7.43e-47: 179: 14.20
+	Mm
		593489 KPCA_MOUSE (1-683): 0: 716: 69.01		ANS1B_MOUSE (12-230): 5.35e-41: 164: 18.67
+	Mm
		934633 KPCB_MOUSE (1-681): 0: 714: 67.50		ANS1B_MOUSE (12-230): 5.35e-41: 164: 18.67
+	Hs
		957223 AKT3_HUMAN (212-677): 1.68e-151: 449: 34.25		DAB2_HUMAN (1-770): 3.91e-90: 301: 100.00
+	Hs
		682217 AKT2_HUMAN (215-677): 5.47e-153: 453: 33.33		DP13A_HUMAN (15-259): 1.71e-36: 148: 11.91
+	Hs
		682064 AKT1_HUMAN (215-677): 1.23e-151: 450: 33.68		DP13A_HUMAN (15-259): 1.71e-36: 148: 11.91
+	Hs
		1356444 AKT3_HUMAN (212-677): 1.68e-151: 449: 34.25		DP13A_HUMAN (15-259): 1.71e-36: 148: 11.91
+	Hs
		957168 KPCD_HUMAN (3-166): 8.84e-63: 223: 38.60		DAB2_HUMAN (1-770): 3.91e-90: 301: 100.00
+	Hs
		833582 KPCE_HUMAN (3-262): 3.13e-57: 209: 34.07		NUMB_HUMAN (22-635): 7.43e-47: 179: 14.20
+	Hs
		554297 KPCD_HUMAN (3-166): 8.84e-63: 223: 38.60		MUC1_HUMAN (320-766): 7.89e-22: 103: 14.16
+	Hs
		833586 KPCZ_HUMAN (21-85): 2.64e-10: 65.5: 36.92		NUMB_HUMAN (22-635): 7.43e-47: 179: 14.20
+	Dm
		54643 APKC_DROME (5-85): 5.11e-13: 74.3: 38.27		NUMB_DROME (24-530): 3.9e-41: 160: 12.25
+	Hs
		983940 KPCZ_HUMAN (21-85): 2.64e-10: 65.5: 36.92		DP13A_HUMAN (15-259): 1.71e-36: 148: 11.91
+	Ce
		1090590 KPC3_CAEEL (21-92): 1.95e-11: 69.3: 40.28		NUMB1_CAEEL (23-530): 3.63e-34: 140: 11.50