HitPredict

Interactor 1: ADT2 (P05141)
ADP/ATP translocase 2 (ADP,ATP carrier protein 2) (ADP,ATP carrier protein, fibroblast isoform) (Adenine nucleotide translocator 2) (ANT 2) (Solute carrier family 25 member 5) [Cleaved into: ADP/ATP translocase 2, N-terminally processed]
Gene: SLC25A5

Interactor 2: IKBA (P25963)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3)
Gene: NFKBIA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 317
+	Hs
		518089 ADT1_HUMAN (1-297): 1.24e-113: 331: 89.23		IKBA_HUMAN (1-317): 2.59e-84: 258: 100.00
+	Hs
		397329 ADT2_HUMAN (1-298): 6.33e-116: 337: 100.00		RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31
+	Hs
		397507 ADT2_HUMAN (1-298): 6.33e-116: 337: 100.00		Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31
+	Hs
		518299 ADT3_HUMAN (1-296): 4.83e-115: 335: 92.57		RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31
+	Hs
		518487 ADT3_HUMAN (1-296): 4.83e-115: 335: 92.57		Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31
+	Hs
		397263 ADT2_HUMAN (1-298): 6.33e-116: 337: 100.00		NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35
+	Hs
		518243 ADT3_HUMAN (1-296): 4.83e-115: 335: 92.57		NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35
+	Hs
		518082 ADT1_HUMAN (1-297): 1.24e-113: 331: 89.23		NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35
+	Hs
		883665 S2513_HUMAN (2-104): 5.95e-22: 97.6: 27.18		RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31
+	Hs
		1330875 S2513_HUMAN (2-104): 5.95e-22: 97.6: 27.18		Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31
+	Hs
		274519 S2512_HUMAN (2-119): 2.57e-20: 92.9: 21.01		RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31
+	Hs
		274627 S2512_HUMAN (2-119): 2.57e-20: 92.9: 21.01		Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31
+	Hs
		1021471 S2513_HUMAN (2-104): 5.95e-22: 97.6: 27.18		ANK3_HUMAN (1-130): 1.86e-30: 123: 10.77
+	Hs
		587743 S2513_HUMAN (2-104): 5.95e-22: 97.6: 27.18		NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35
+	Hs
		274490 S2512_HUMAN (2-119): 2.57e-20: 92.9: 21.01		NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35