Protein: Q6AXH7
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356)

Gene: Q6AXH7, Ezh2
Organism: Mus musculus
Interactions: 128
UniProt ID: Q6AXH7

Gene Ontology (top 5):
GO:0003682 - chromatin binding
GO:0031507 - heterochromatin formation
GO:0032259 - methylation
GO:0035098 - ESC/E(Z) complex
GO:0048511 - rhythmic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1149770

SUZ12
Polycomb protein Suz12

1

11

High-throughput

0.691

High

1141935

RBBP4
Histone-binding protein RBBP4

1

20

High-throughput

0.575

High

1141960

RBBP7
Histone-binding protein RBBP7

1

20

High-throughput

0.575

High

1149787

EED
Polycomb protein EED

1

20

High-throughput

0.575

High

222998

COPB2
Coatomer subunit beta'

1

10

High-throughput

0.514

High

291903

O88568
Heterogenous nuclear ribonucleoprotein U

1

13

High-throughput

0.514

High

952754

H33
Histone H3.3

1

20

High-throughput

0.514

High

1110537

Q3TAU7
Coatomer subunit alpha

1

12

High-throughput

0.514

High

936404

HDAC2
Histone deacetylase 2

1

20

High-throughput

0.484

High

1125396

Q5DTP7
DNA helicase

1

20

High-throughput

0.484

High

539735

LMNB1
Lamin-B1

1

17

High-throughput

0.445

High

1141047

SIN3A
Paired amphipathic helix protein Sin3a

1

4

High-throughput

0.445

High

1143820

TIF1B
Transcription intermediary factor 1-beta

1

20

High-throughput

0.445

High

1149779

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

1

High-throughput

0.445

High

1149788

TADBP
TAR DNA-binding protein 43

1

11

High-throughput

0.445

High

1149795

RENT1
Regulator of nonsense transcripts 1

1

6

High-throughput

0.445

High

1149808

AEBP2
Zinc finger protein AEBP2

1

19

High-throughput

0.445

High

49106

A0PJE6
Propionyl-CoA carboxylase beta chain, mitochondrial

1

2

High-throughput

0.407

High

192244

PHB2
Prohibitin-2

1

2

High-throughput

0.407

High

223165

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

4

High-throughput

0.407

High

291914

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

13

High-throughput

0.407

High

427723

ANXA2
Annexin A2

1

7

High-throughput

0.407

High

430509

K2C4
Keratin, type II cytoskeletal 4

1

9

High-throughput

0.407

High

432436

HS90A
Heat shock protein HSP 90-alpha

1

10

High-throughput

0.407

High

435926

ENPL
Endoplasmin

1

10

High-throughput

0.407

High

444564

K1C13
Keratin, type I cytoskeletal 13

1

15

High-throughput

0.407

High

486105

EF1A1
Elongation factor 1-alpha 1

1

3

High-throughput

0.407

High

516942

TCPA
T-complex protein 1 subunit alpha

1

20

High-throughput

0.407

High

535306

RS16
Small ribosomal subunit protein uS9

1

2

High-throughput

0.407

High

566055

ENOA
Alpha-enolase

1

4

High-throughput

0.407

High

580496

FAS
Fatty acid synthase

1

3

High-throughput

0.407

High

581915

SERPH
Serpin H1

1

5

High-throughput

0.407

High

588721

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.407

High

589636

VIME
Vimentin

1

11

High-throughput

0.407

High

677643

CTND1
Catenin delta-1

1

10

High-throughput

0.407

High

723807

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

3

High-throughput

0.407

High

724491

CALX
Calnexin

1

2

High-throughput

0.407

High

727687

PRDX1
Peroxiredoxin-1

1

5

High-throughput

0.407

High

729721

RL12
Large ribosomal subunit protein uL11

1

1

High-throughput

0.407

High

751924

GRP75
Stress-70 protein, mitochondrial

1

9

High-throughput

0.407

High

792275

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.407

High

823130

ADT1
ADP/ATP translocase 1

1

7

High-throughput

0.407

High

825786

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

12

High-throughput

0.407

High

831949

MCM4
DNA replication licensing factor MCM4

1

9

High-throughput

0.407

High

837577

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

3

High-throughput

0.407

High

851097

ADT2
ADP/ATP translocase 2

1

7

High-throughput

0.407

High

854532

KPYM
Pyruvate kinase PKM

1

2

High-throughput

0.407

High

862352

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

7

High-throughput

0.407

High

880622

ATPB
ATP synthase subunit beta, mitochondrial

1

4

High-throughput

0.407

High

885070

EF1D
Elongation factor 1-delta

1

2

High-throughput

0.407

High

885098

RU2A
U2 small nuclear ribonucleoprotein A'

1

3

High-throughput

0.407

High

885403

EF2
Elongation factor 2

1

3

High-throughput

0.407

High

888071

RUVB1
RuvB-like 1

1

8

High-throughput

0.407

High

888814

PCBP1
Poly(rC)-binding protein 1

1

10

High-throughput

0.407

High

904273

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

10

High-throughput

0.407

High

912771

SMD3
Small nuclear ribonucleoprotein Sm D3

1

3

High-throughput

0.407

High

919330

RAN
GTP-binding nuclear protein Ran

1

9

High-throughput

0.407

High

922780

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.407

High

926138

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.407

High

926311

CH60
60 kDa heat shock protein, mitochondrial

1

15

High-throughput

0.407

High

936158

IMB1
Importin subunit beta-1

1

6

High-throughput

0.407

High

936681

ELAV1
ELAV-like protein 1

1

4

High-throughput

0.407

High

945919

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.407

High

945948

TCPD
T-complex protein 1 subunit delta

1

20

High-throughput

0.407

High

945980

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.407

High

945989

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.407

High

952203

SRSF3
Serine/arginine-rich splicing factor 3

1

20

High-throughput

0.407

High

956271

PKP1
Plakophilin-1

1

11

High-throughput

0.407

High

958394

TBB5
Tubulin beta-5 chain

1

5

High-throughput

0.407

High

970213

PLAK
Junction plakoglobin

1

13

High-throughput

0.407

High

975782

ATPA
ATP synthase subunit alpha, mitochondrial

1

6

High-throughput

0.407

High

985163

PYC
Pyruvate carboxylase, mitochondrial

1

4

High-throughput

0.407

High

1012212

K2C80
Keratin, type II cytoskeletal 80

1

8

High-throughput

0.407

High

1094038

Q20BD0
Heterogeneous nuclear ribonucleoprotein A/B

1

13

High-throughput

0.407

High

1111861

Q3TH47
Ubiquitin-like domain-containing protein

1

8

High-throughput

0.407

High

1112397

Q3U6P5
RRM domain-containing protein

1

13

High-throughput

0.407

High

1112942

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

2

High-throughput

0.407

High

1114081

Q3ZAW8
Keratin 16

1

15

High-throughput

0.407

High

1131548

Q5SVJ0
calcium/calmodulin-dependent protein kinase

1

1

High-throughput

0.407

High

1131961

ACACA
Acetyl-CoA carboxylase 1

1

6

High-throughput

0.407

High

1141085

ODO1
2-oxoglutarate dehydrogenase complex component E1

1

2

High-throughput

0.407

High

1142252

ARGI1
Arginase-1

1

2

High-throughput

0.407

High

1144847

RALY
RNA-binding protein Raly

1

8

High-throughput

0.407

High

1149762

K2C73
Keratin, type II cytoskeletal 73

1

8

High-throughput

0.407

High

1149763

ODBB
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial

1

4

High-throughput

0.407

High

1149764

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

8

High-throughput

0.407

High

1149765

Q6P9L1
Cad protein

1

4

High-throughput

0.407

High

1149766

Q71LX8
Heat shock protein HSP 90-beta

1

10

High-throughput

0.407

High

1149767

SND1
Staphylococcal nuclease domain-containing protein 1

1

2

High-throughput

0.407

High

1149768

Q7M754
trypsin

1

3

High-throughput

0.407

High

1149769

DSG1B
Desmoglein-1-beta

1

2

High-throughput

0.407

High

1149771

SEPT9
Septin-9

1

5

High-throughput

0.407

High

1149772

EFTU
Elongation factor Tu, mitochondrial

1

5

High-throughput

0.407

High

1149773

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

11

High-throughput

0.407

High

1149774

ODPX
Pyruvate dehydrogenase protein X component, mitochondrial

1

7

High-throughput

0.407

High

1149775

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

7

High-throughput

0.407

High

1149776

FLNA
Filamin-A

1

9

High-throughput

0.407

High

1149777

TOX4
TOX high mobility group box family member 4

1

20

High-throughput

0.407

High

1149778

MYEF2
Myelin expression factor 2

1

8

High-throughput

0.407

High

1149780

MATR3
Matrin-3

1

5

High-throughput

0.407

High

1149781

SF3A1
Splicing factor 3A subunit 1

1

13

High-throughput

0.407

High

1149782

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

4

High-throughput

0.407

High

1149783

ATPG
ATP synthase subunit gamma, mitochondrial

1

1

High-throughput

0.407

High

1149784

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.407

High

1149785

PRP6
Pre-mRNA-processing factor 6

1

12

High-throughput

0.407

High

1149786

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

1

5

High-throughput

0.407

High

1149789

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

4

High-throughput

0.407

High

1149790

PRP8
Pre-mRNA-processing-splicing factor 8

1

1

High-throughput

0.407

High

1149791

Q9CV95
Uncharacterized protein

1

15

High-throughput

0.407

High

1149792

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

4

High-throughput

0.407

High

1149793

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

7

High-throughput

0.407

High

1149794

U2AF1
Splicing factor U2AF 35 kDa subunit

1

3

High-throughput

0.407

High

1149797

GTF2I
General transcription factor II-I

1

2

High-throughput

0.407

High

1149798

COPB
Coatomer subunit beta

1

2

High-throughput

0.407

High

1149799

RL38
Large ribosomal subunit protein eL38

1

2

High-throughput

0.407

High

1149801

K1C17
Keratin, type I cytoskeletal 17

1

13

High-throughput

0.407

High

1149802

PLEC
Plectin

1

7

High-throughput

0.407

High

1149803

MAGD1
Melanoma-associated antigen D1

1

8

High-throughput

0.407

High

1149804

RUVB2
RuvB-like 2

1

8

High-throughput

0.407

High

1149805

RBMX
RNA-binding motif protein, X chromosome

1

10

High-throughput

0.407

High

1149806

NU160
Nuclear pore complex protein Nup160

1

1

High-throughput

0.407

High

1149807

ILF3
Interleukin enhancer-binding factor 3

1

8

High-throughput

0.407

High

139780

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

572073

LYZ1
Lysozyme C-1

1

0

High-throughput

0.232

Low

621969

CATA
Catalase

1

0

High-throughput

0.232

Low

1119813

Q52L67
Gpsn2 protein

1

0

High-throughput

0.232

Low

1149796

GSDMA
Gasdermin-A

1

0

High-throughput

0.232

Low

1149800

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024