Interactor 1: HP1 (P05205)
Heterochromatin protein 1 (HP1) (Non-histone chromosomal protein C1A9 antigen)
Gene: Su(var)205

Interactor 2: HP1 (P05205)
Heterochromatin protein 1 (HP1) (Non-histone chromosomal protein C1A9 antigen)
Gene: Su(var)205

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.873

The method score is based on:

Property Details
Experiments 21472955, 11566886, 20498723, 30659116
Identification Methods x-ray crystallography, pull down, affinity chromatography technology
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Chromo~Chromo, Chromo_shadow~Chromo_shadow
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000182 - rDNA binding
GO:0000278 - mitotic cell cycle
GO:0000723 - telomere maintenance
GO:0000775 - chromosome, centromeric region
and 37 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 206
Dm

1 206
+ Dm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Dm
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024