Protein: TMPS5
Transmembrane protease serine 5 (EC 3.4.21.-) (Spinesin)

Gene: TMPS5, TMPRSS5
Organism: Homo sapiens
Interactions: 47
UniProt ID: Q9H3S3

Gene Ontology (top 5):
GO:0004252 - serine-type endopeptidase activity
GO:0005886 - plasma membrane
GO:0006508 - proteolysis
GO:0008233 - peptidase activity
GO:0043025 - neuronal cell body

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1286575

AGRG6
Adhesion G-protein coupled receptor G6

1

4

High-throughput

0.691

High

1432879

C42S2
CDC42 small effector protein 2

2

1

High-throughput

0.611

High

1368832

N42L2
NEDD4-binding protein 2-like 2

3

1

High-throughput

0.604

High

332244

UCP5
Brain mitochondrial carrier protein 1

1

13

High-throughput

0.536

High

408162

TBB4A
Tubulin beta-4A chain

1

15

High-throughput

0.536

High

427944

ICAM1
Intercellular adhesion molecule 1

1

1

High-throughput

0.536

High

535541

BIP
Endoplasmic reticulum chaperone BiP

1

8

High-throughput

0.536

High

537900

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.536

High

931108

HSP72
Heat shock-related 70 kDa protein 2

1

1

High-throughput

0.536

High

943131

STX17
Syntaxin-17

1

1

High-throughput

0.536

High

1108704

TBB3
Tubulin beta-3 chain

1

15

High-throughput

0.536

High

1259499

TBA1A
Tubulin alpha-1A chain

1

12

High-throughput

0.536

High

170960

CLGN
Calmegin

1

10

High-throughput

0.489

High

354396

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

10

High-throughput

0.489

High

457693

TBB5
Tubulin beta chain

1

15

High-throughput

0.489

High

665142

COT2
COUP transcription factor 2

1

5

High-throughput

0.489

High

997132

TBA4A
Tubulin alpha-4A chain

1

11

High-throughput

0.489

High

997509

TBB4B
Tubulin beta-4B chain

1

15

High-throughput

0.489

High

1118591

TBB2A
Tubulin beta-2A chain

1

15

High-throughput

0.489

High

1125658

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

2

High-throughput

0.489

High

1133229

STAR3
StAR-related lipid transfer protein 3

1

1

High-throughput

0.489

High

1191978

TBB8
Tubulin beta-8 chain

1

15

High-throughput

0.489

High

1235422

ACD10
Acyl-CoA dehydrogenase family member 10

1

1

High-throughput

0.489

High

1349169

S2540
Mitochondrial glutathione transporter SLC25A40

1

11

High-throughput

0.489

High

1364112

TM9S4
Transmembrane 9 superfamily member 4

1

7

High-throughput

0.489

High

1410591

TBA1C
Tubulin alpha-1C chain

1

13

High-throughput

0.489

High

1414189

TBB6
Tubulin beta-6 chain

1

15

High-throughput

0.489

High

1415041

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

1

7

High-throughput

0.489

High

1430563

LMA2L
VIP36-like protein

1

6

High-throughput

0.489

High

1432881

CLN6
Ceroid-lipofuscinosis neuronal protein 6

1

2

High-throughput

0.489

High

1432883

DD19B
ATP-dependent RNA helicase DDX19B

1

3

High-throughput

0.489

High

1015121

ARF5
ADP-ribosylation factor 5

1

3

High-throughput

0.479

High

1432884

FBX7
F-box only protein 7

1

1

High-throughput

0.457

High

840791

RS27
Small ribosomal subunit protein eS27

1

1

High-throughput

0.437

High

1036386

BDH
D-beta-hydroxybutyrate dehydrogenase, mitochondrial

1

4

High-throughput

0.437

High

1137155

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

2

High-throughput

0.437

High

1238685

TM214
Transmembrane protein 214

1

2

High-throughput

0.437

High

1432877

TOR3A
Torsin-3A

1

13

High-throughput

0.437

High

1030427

DIAC
Di-N-acetylchitobiase

1

0

High-throughput

0.279

Low

1060297

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

1

0

High-throughput

0.279

Low

1238227

GPAT2
Glycerol-3-phosphate acyltransferase 2, mitochondrial

1

0

High-throughput

0.279

Low

1335592

CHSTE
Carbohydrate sulfotransferase 14

1

0

High-throughput

0.279

Low

1432878

TRABD
TraB domain-containing protein

1

0

High-throughput

0.279

Low

1432880

DECR2
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

1

0

High-throughput

0.279

Low

1432882

PISD
Phosphatidylserine decarboxylase proenzyme, mitochondrial

1

0

High-throughput

0.279

Low

946530

YBEY
Endoribonuclease YbeY

1

0

High-throughput

0.249

Low

431609

AP2A
Transcription factor AP-2-alpha

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025