HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: TCPQ (P50990)
T-complex protein 1 subunit theta (TCP-1-theta) (EC 3.6.1.-) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15)
Gene: CCT8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.703

Property	Details
Experiments	25852190, 31980649, 36244648, unassigned2173, 37045861
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 648 Hs			1 548
+	Hs
		401367 RAF1_HUMAN (1-648): 0: 637: 100.00		TCPH_HUMAN (9-538): 0: 564: 26.39
+	Hs
		400477 RAF1_HUMAN (1-648): 0: 637: 100.00		TCPG_HUMAN (10-547): 0: 558: 28.21
+	Hs
		400468 RAF1_HUMAN (1-648): 0: 637: 100.00		TCPE_HUMAN (2-524): 0: 535: 29.62
+	Hs
		400498 RAF1_HUMAN (1-648): 0: 637: 100.00		TCPD_HUMAN (19-525): 0: 530: 28.24
+	Hs
		400245 RAF1_HUMAN (1-648): 0: 637: 100.00		TCPA_HUMAN (21-541): 0: 528: 29.89
+	Hs
		521254 ARAF_HUMAN (44-646): 8.15e-165: 486: 59.18		TCPQ_HUMAN (1-548): 0: 616: 100.00
+	Zm
		26201 A0A1D6IZ90_MAIZE (77-608): 2.51e-153: 458: 18.30		A0AAJ8WYQ6_MAIZE (10-543): 0: 612: 52.22
+	Hs
		578538 BRAF_HUMAN (39-647): 9.6e-166: 494: 56.02		TCPH_HUMAN (9-538): 0: 564: 26.39
+	Hs
		521423 ARAF_HUMAN (44-646): 8.15e-165: 486: 59.18		TCPH_HUMAN (9-538): 0: 564: 26.39
+	Hs
		521249 ARAF_HUMAN (44-646): 8.15e-165: 486: 59.18		TCPG_HUMAN (10-547): 0: 558: 28.21
+	Hs
		521255 ARAF_HUMAN (44-646): 8.15e-165: 486: 59.18		TCPD_HUMAN (19-525): 0: 530: 28.24
+	Hs
		521195 ARAF_HUMAN (44-646): 8.15e-165: 486: 59.18		TCPA_HUMAN (21-541): 0: 528: 29.89
+	Hs
		440449 FYN_HUMAN (337-607): 1.87e-103: 326: 34.55		TCPQ_HUMAN (1-548): 0: 616: 100.00
+	Hs
		463025 YES_HUMAN (329-607): 9.75e-106: 332: 33.92		TCPG_HUMAN (10-547): 0: 558: 28.21
+	Hs
		440443 FYN_HUMAN (337-607): 1.87e-103: 326: 34.55		TCPG_HUMAN (10-547): 0: 558: 28.21
+	Hs
		440441 FYN_HUMAN (337-607): 1.87e-103: 326: 34.55		TCPE_HUMAN (2-524): 0: 535: 29.62
+	Hs
		462980 YES_HUMAN (329-607): 9.75e-106: 332: 33.92		TCPA_HUMAN (21-541): 0: 528: 29.89
+	Hs
		440450 FYN_HUMAN (337-607): 1.87e-103: 326: 34.55		TCPD_HUMAN (19-525): 0: 530: 28.24
+	Hs
		440350 FYN_HUMAN (337-607): 1.87e-103: 326: 34.55		TCPA_HUMAN (21-541): 0: 528: 29.89
+	Hs
		1309238 KSR1_HUMAN (138-648): 4.19e-108: 349: 24.61		TCPQM_HUMAN (32-545): 7.53e-75: 249: 32.17