HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: EIF3A (Q14152)
Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta) (eIF3 p167) (eIF3 p180) (eIF3 p185)
Gene: EIF3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37045861
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 1382
+	Hs
		400389 RAF1_HUMAN (1-648): 0: 637: 100.00		MYH10_HUMAN (16-1091): 5.14e-43: 174: 10.13
+	Hs
		400485 RAF1_HUMAN (1-648): 0: 637: 100.00		YLPM1_HUMAN (774-1359): 6.65e-43: 174: 21.91
+	Hs
		400388 RAF1_HUMAN (1-648): 0: 637: 100.00		MYH9_HUMAN (72-1154): 3.11e-41: 168: 8.84
+	Hs
		401052 RAF1_HUMAN (1-648): 0: 637: 100.00		MYH14_HUMAN (461-1365): 9.31e-32: 137: 11.66
+	Hs
		400862 RAF1_HUMAN (1-648): 0: 637: 100.00		PLEC_HUMAN (497-1343): 1.74e-18: 94.5: 13.97
+	Hs
		401684 RAF1_HUMAN (1-648): 0: 637: 100.00		MYH13_HUMAN (849-1382): 1.07e-16: 88.5: 7.09
+	Hs
		401772 RAF1_HUMAN (1-648): 0: 637: 100.00		MRCKB_HUMAN (610-1125): 1.23e-14: 81.6: 10.73
+	Hs
		400392 RAF1_HUMAN (1-648): 0: 637: 100.00		MYH11_HUMAN (17-549): 4.98e-09: 63.4: 8.61
+	Hs
		521307 ARAF_HUMAN (44-646): 8.15e-165: 486: 59.18		MAP1A_HUMAN (494-1117): 2.9e-30: 133: 13.68
+	Dm
		541249 KRAF1_DROME (45-647): 8.65e-166: 494: 44.98		Q9W179_DROME (592-980): 9e-10: 65.7: 16.92
+	Dm
		541212 KRAF1_DROME (45-647): 8.65e-166: 494: 44.98		Q8MLP1_DROME (578-902): 6.9e-09: 63: 17.94
+	Hs
		521398 ARAF_HUMAN (44-646): 8.15e-165: 486: 59.18		MY18A_HUMAN (532-955): 1.35e-09: 65.3: 16.18
+	Hs
		117127 J3QRU1_HUMAN (329-607): 1.13e-105: 332: 33.92		MYH9_HUMAN (72-1154): 3.11e-41: 168: 8.84
+	Hs
		463006 YES_HUMAN (329-607): 9.75e-106: 332: 33.92		MYH9_HUMAN (72-1154): 3.11e-41: 168: 8.84
+	Hs
		440414 FYN_HUMAN (337-607): 1.87e-103: 326: 34.55		MYH9_HUMAN (72-1154): 3.11e-41: 168: 8.84
+	Hs
		440576 FYN_HUMAN (337-607): 1.87e-103: 326: 34.55		ITSN1_HUMAN (539-880): 4.78e-22: 106: 18.54
+	Hs
		557552 SRC_HUMAN (331-607): 2.21e-106: 334: 33.45		MYH4_HUMAN (849-1382): 1.4e-17: 91.6: 8.05
+	Hs
		440658 FYN_HUMAN (337-607): 1.87e-103: 326: 34.55		MY18A_HUMAN (532-955): 1.35e-09: 65.3: 16.18