HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: SMU1 (Q2TAY7)
WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed]
Gene: SMU1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 513
+	Hs
		400592 RAF1_HUMAN (1-648): 0: 637: 100.00		WDR5_HUMAN (78-425): 4.43e-77: 247: 20.96
+	Hs
		401279 RAF1_HUMAN (1-648): 0: 637: 100.00		SNR40_HUMAN (51-333): 5.1e-39: 147: 14.34
+	Mm
		700363 BRAF_MOUSE (38-647): 4.12e-164: 490: 55.84		WDR26_MOUSE (3-513): 9.21e-90: 289: 19.30
+	Hs
		400994 RAF1_HUMAN (1-648): 0: 637: 100.00		Q6FHM2_HUMAN (187-335): 2.67e-21: 96.9: 20.81
+	Hs
		578540 BRAF_HUMAN (39-647): 9.6e-166: 494: 56.02		TBL1R_HUMAN (252-512): 1.1e-62: 214: 16.96
+	Hs
		400627 RAF1_HUMAN (1-648): 0: 637: 100.00		RACK1_HUMAN (277-377): 7.28e-11: 65.5: 33.33
+	Hs
		400614 RAF1_HUMAN (1-648): 0: 637: 100.00		GBB2_HUMAN (431-511): 1.7e-10: 64.5: 12.35
+	Hs
		521298 ARAF_HUMAN (44-646): 8.15e-165: 486: 59.18		RACK1_HUMAN (277-377): 7.28e-11: 65.5: 33.33
+	Hs
		440671 FYN_HUMAN (337-607): 1.87e-103: 326: 34.55		SNR40_HUMAN (51-333): 5.1e-39: 147: 14.34
+	Hs
		557207 SRC_HUMAN (331-607): 2.21e-106: 334: 33.45		RACK1_HUMAN (277-377): 7.28e-11: 65.5: 33.33
+	Hs
		440482 FYN_HUMAN (337-607): 1.87e-103: 326: 34.55		RACK1_HUMAN (277-377): 7.28e-11: 65.5: 33.33
+	Hs
		1250423 KSR2_HUMAN (332-623): 6.75e-43: 168: 34.43		TBL1R_HUMAN (252-512): 1.1e-62: 214: 16.96