HitPredict

Interactor 1: JUN (P05412)
Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)
Gene: JUN

Interactor 2: M3K1 (Q13233)
Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) (EC 2.3.2.27)
Gene: MAP3K1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.50	0.543

Property	Details
Experiments	26237449, 12796506
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 331 Hs			1 1512
+	Mm
		101504 JUN_MOUSE (1-331): 5.76e-86: 263: 94.61		F8VQ72_MOUSE (1-1512): 0: 1937: 88.41
+	Rn
		624771 JUNB_RAT (1-331): 1.47e-72: 229: 44.26		M3K1_RAT (1-1512): 0: 1942: 89.16
+	Hs
		566761 JUNB_HUMAN (1-331): 3.94e-63: 205: 43.89		PKN2_HUMAN (785-1509): 6.77e-150: 485: 16.27
+	Hs
		402037 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		KPCD1_HUMAN (852-1510): 2.29e-124: 413: 16.89
+	Hs
		625260 CEBPG_HUMAN (215-318): 4.54e-10: 59.3: 22.86		CDK2_HUMAN (1243-1509): 1.1e-104: 337: 25.85
+	Hs
		570002 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		M3K3_HUMAN (1243-1505): 1.2e-51: 195: 44.03