Interactor 1: ERF3 (P05453)
Eukaryotic peptide chain release factor GTP-binding subunit (EC 3.6.5.-) (ERF-3) (ERF3) (ERF2) (G1 to S phase transition protein 1) (Omnipotent suppressor protein 2) (PSI no more protein 2) (Polypeptide release factor 3) (Translation release factor 3)
Gene: SUP35

Interactor 2: ERF1 (P12385)
Eukaryotic peptide chain release factor subunit 1 (Eukaryotic release factor 1) (eRF1) (Omnipotent suppressor protein 1)
Gene: SUP45

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 7556078, 11805826, 25411355, 24278036, 10376874, 10320572, 16554755, 16429126, 17272721, 18267004, 30873535, 18539146, 14759368, 25023996, 9111351, 15337765, 29139201, 18463713, 37968396
Identification Methods two hybrid, biophysical, coimmunoprecipitation, tandem affinity purification, pull down, affinity chromatography technology, enzymatic study, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains GTP_EFTU~eRF1_1, GTP_EFTU~eRF1_2, GTP_EFTU_D2~eRF1_1, GTP_EFTU_D2~eRF1_2, GTP_EFTU_D3~eRF1_2, GTP_EFTU_D3~eRF1_3
Common GO terms GO:0003747 - translation release factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006415 - translational termination
GO:0010494 - cytoplasmic stress granule
and 1 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 685
Sc

1 437
+ Hs
+ Hs
+ Sc

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Last updated: 15 Jul 2024