Interactor 1: CDC37 (P06101)
Hsp90 co-chaperone Cdc37 (Cell division control protein 37) (Hsp90 chaperone protein kinase-targeting subunit)
Gene: CDC37

Interactor 2: CAK1 (P43568)
Serine/threonine-protein kinase CAK1 (EC 2.7.11.22) (CDK-activating kinase)
Gene: CAK1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.809

The method score is based on:

Property Details
Experiments 12111552, 24452458
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC37_M~Pkinase, CDC37_N~Pkinase
Common GO terms GO:0005737 - cytoplasm
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 506
Sc

1 368
+ Sc
+ Sc
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024