HitPredict

Interactor 1: RL25 (P04456)
Large ribosomal subunit protein uL23 (60S ribosomal protein L25) (RP16L) (YL25) (YP42')
Gene: RPL25

Interactor 2: MAK5 (P38112)
ATP-dependent RNA helicase MAK5 (EC 3.6.4.13) (Maintenance of killer protein 5)
Gene: MAK5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	16429126, 31062022
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 142 Sc			1 773
+	Hs
		978597 RL23A_HUMAN (17-142): 2.69e-59: 182: 62.70		DDX42_HUMAN (16-743): 4.77e-128: 406: 19.89
+	Sc
		409836 RL25_YEAST (1-142): 9.15e-58: 177: 100.00		DED1_YEAST (103-633): 2.39e-128: 397: 23.20
+	Sc
		409950 RL25_YEAST (1-142): 9.15e-58: 177: 100.00		DBP2_YEAST (62-611): 4.01e-126: 389: 21.76
+	Hs
		978713 RL23A_HUMAN (17-142): 2.69e-59: 182: 62.70		DDX24_HUMAN (242-734): 2.15e-67: 241: 33.13
+	Sc
		410022 RL25_YEAST (1-142): 9.15e-58: 177: 100.00		DRS1_YEAST (174-666): 9.23e-41: 162: 29.06
+	Hs
		978657 RL23A_HUMAN (17-142): 2.69e-59: 182: 62.70		DDX27_HUMAN (57-587): 3.81e-39: 157: 27.83
+	Sc
		410314 RL25_YEAST (1-142): 9.15e-58: 177: 100.00		HAS1_YEAST (178-598): 2.56e-41: 160: 31.46
+	Hs
		978755 RL23A_HUMAN (17-142): 2.69e-59: 182: 62.70		DDX18_HUMAN (70-598): 3.27e-38: 153: 29.16
+	Sc
		410108 RL25_YEAST (1-142): 9.15e-58: 177: 100.00		DBP8_YEAST (178-619): 1.58e-39: 153: 29.33