Interactor 1: UBC2 (P06104)
Ubiquitin-conjugating enzyme E2 2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Radiation sensitivity protein 6) (Ubiquitin carrier protein UBC2) (Ubiquitin-protein ligase UBC2)
Gene: RAD6

Interactor 2: UBR1 (P19812)
E3 ubiquitin-protein ligase UBR1 (EC 2.3.2.27) (N-end-recognizing protein) (N-recognin-1) (RING-type E3 ubiquitin transferase UBR1)
Gene: UBR1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.763

The method score is based on:

Property Details
Experiments 10581257, 8505328, 19164530, 8436296, 12391316, 12535539, 37968396, 36162503, 7926769, 10850718, 1651502, 28515311, 34789879, 21076411, 21179020
Identification Methods affinity chromatography technology, two hybrid, coimmunoprecipitation, pull down, enzymatic study, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0016567 - protein ubiquitination
GO:0036503 - ERAD pathway
and 5 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 172
Sc

1 1950
+ Sc
+ Hs
+ Hs
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+ Hs
+ Hs
+ Rn
+ Hs
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+ Ce
+ Hs
+ Hs
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+ Pf

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Last updated: 15 Jul 2024