Interactor 1: INSR (P06213)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR
Interactor 2: INSR (P06213)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.93 | 1.00 | 0.969 |
The method score is based on:
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | fn3~fn3, Furin-like~fn3, PK_Tyr_Ser-Thr~fn3, Recep_L_domain~fn3, Furin-like~Furin-like, Furin-like~Recep_L_domain, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, Recep_L_domain~Recep_L_domain |
Common GO terms | GO:0001540 - amyloid-beta binding GO:0001934 - positive regulation of protein phosphorylation GO:0002092 - positive regulation of receptor internalization GO:0003007 - heart morphogenesis GO:0004713 - protein tyrosine kinase activity and 68 others more... |
Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024