HitPredict

Interactor 1: INSR (P06213)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Interactor 2: DNJA3 (Q96EY1)
DnaJ homolog subfamily A member 3, mitochondrial (DnaJ protein Tid-1) (hTid-1) (Hepatocellular carcinoma-associated antigen 57) (Tumorous imaginal discs protein Tid56 homolog)
Gene: DNAJA3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0044877 - protein-containing complex binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1382 Hs			1 480
+	Hs
		435729 IGF1R_HUMAN (31-1380): 0: 1353: 56.11		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		411313 INSR_HUMAN (1-1382): 0: 1530: 100.00		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243254 INSR_HUMAN (1-1382): 0: 1530: 100.00		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		435551 IGF1R_HUMAN (31-1380): 0: 1353: 56.11		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243262 IGF1R_HUMAN (31-1380): 0: 1353: 56.11		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Dm
		448256 INSR_DROME (30-1382): 0: 1002: 34.55		Q9VFV9_DROME (89-469): 4.7e-111: 335: 23.19
+	Hs
		383929 ERBB2_HUMAN (978-1381): 5.36e-93: 330: 25.67		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		666634 LTK_HUMAN (1013-1291): 2e-71: 259: 44.52		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Mm
		1142038 MUSK_MOUSE (1017-1291): 3.2e-70: 256: 42.56		DNJA3_MOUSE (1-480): 0: 555: 87.50
+	Hs
		385330 NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		1081563 NTRK3_HUMAN (996-1290): 1.93e-64: 238: 39.43		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		609471 FGFR3_HUMAN (1015-1287): 2.21e-62: 231: 40.78		DNJA3_HUMAN (1-480): 0: 553: 100.00
+	Hs
		383639 ERBB2_HUMAN (978-1381): 5.36e-93: 330: 25.67		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243250 ERBB2_HUMAN (978-1381): 5.36e-93: 330: 25.67		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		243669 ALK_HUMAN (982-1339): 1.96e-70: 263: 40.53		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		384352 NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243251 NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		681463 NTRK3_HUMAN (996-1290): 1.93e-64: 238: 39.43		DNJA1_HUMAN (89-468): 2.73e-123: 367: 26.43
+	Hs
		243425 NTRK3_HUMAN (996-1290): 1.93e-64: 238: 39.43		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38
+	Hs
		243305 UFO_HUMAN (789-1294): 1.77e-61: 229: 31.09		DNJA2_HUMAN (89-465): 4.81e-122: 364: 26.38