HitPredict

Interactor 1: INSR (P06213)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Interactor 2: DDRGK (Q96HY6)
DDRGK domain-containing protein 1 (Dashurin) (UFM1-binding and PCI domain-containing protein 1)
Gene: DDRGK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008284 - positive regulation of cell population proliferation GO:0030335 - positive regulation of cell migration
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1382 Hs			1 314
+	Hs
		435731 IGF1R_HUMAN (31-1380): 0: 1353: 56.11		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		665514 EPHA8_HUMAN (644-1322): 3.66e-168: 531: 20.68		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		445868 ROS1_HUMAN (511-1377): 3.38e-158: 530: 22.63		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		1294127 ALK_HUMAN (982-1339): 1.96e-70: 263: 40.53		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		1081567 NTRK3_HUMAN (996-1290): 1.93e-64: 238: 39.43		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00