Interactor 1: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK
Interactor 2: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.89 | 1.00 | 0.948 |
The method score is based on:
Property | Details |
---|---|
Experiments | 9533446, 31980649, 20372794, 16461343, 24463463, 17118402 |
Identification Methods | enzymatic study, affinity chromatography technology, protein kinase assay, x-ray crystallography, cosedimentation in solution, fluorescence technology |
Interaction Type | direct interaction, physical association, phosphorylation reaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1, SH2~SH2, SH2~SH3_1, SH3_1~SH3_1 |
Common GO terms | GO:0000242 - pericentriolar material GO:0001772 - immunological synapse GO:0001784 - phosphotyrosine residue binding GO:0004713 - protein tyrosine kinase activity GO:0004715 - non-membrane spanning protein tyrosine kinase activity and 42 others more... |
Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores
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Last updated: 15 Jul 2024