HitPredict

Interactor 1: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Interactor 2: RHG17 (Q68EM7)
Rho GTPase-activating protein 17 (Rho-type GTPase-activating protein 17) (RhoGAP interacting with CIP4 homologs protein 1) (RICH-1)
Gene: ARHGAP17

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	11431473
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 509 Hs			1 881
+	Hs
		523026 SRC_HUMAN (20-507): 0: 586: 55.00		RHG17_HUMAN (1-881): 4.48e-144: 450: 100.00
+	Hs
		337492 ABL1_HUMAN (49-502): 8.1e-171: 513: 42.21		RHG17_HUMAN (1-881): 4.48e-144: 450: 100.00
+	Hs
		986382 BTK_HUMAN (7-505): 1.49e-167: 490: 33.27		RHG17_HUMAN (1-881): 4.48e-144: 450: 100.00
+	Hs
		411755 LCK_HUMAN (1-509): 0: 661: 100.00		RHG21_HUMAN (10-685): 1.4e-69: 254: 16.46
+	Hs
		442896 HCK_HUMAN (1-509): 0: 602: 65.04		3BP1_HUMAN (1-651): 7.85e-80: 274: 35.91
+	Hs
		523225 SRC_HUMAN (20-507): 0: 586: 55.00		3BP1_HUMAN (1-651): 7.85e-80: 274: 35.91
+	Hs
		433814 LYN_HUMAN (1-509): 0: 582: 62.72		RHG21_HUMAN (10-685): 1.4e-69: 254: 16.46
+	Mm
		763398 FYN_MOUSE (30-507): 0: 586: 58.80		RHG33_MOUSE (210-751): 3.35e-68: 249: 20.50
+	Hs
		433879 LYN_HUMAN (1-509): 0: 582: 62.72		RHG12_HUMAN (53-427): 1.04e-63: 232: 17.90
+	Mm
		337622 ABL1_MOUSE (49-502): 5.34e-171: 513: 42.21		3BP1_MOUSE (1-618): 1.8e-83: 284: 38.35
+	Hs
		337603 ABL1_HUMAN (49-502): 8.1e-171: 513: 42.21		3BP1_HUMAN (1-651): 7.85e-80: 274: 35.91
+	Hs
		337453 ABL1_HUMAN (49-502): 8.1e-171: 513: 42.21		ABR_HUMAN (1-412): 3.62e-71: 253: 19.17
+	Hs
		64641 LCK_HUMAN (1-509): 0: 661: 100.00		RHG32_HUMAN (250-462): 7.37e-18: 91.3: 29.41
+	Hs
		442768 HCK_HUMAN (1-509): 0: 602: 65.04		BCR_HUMAN (250-408): 2.36e-16: 86.3: 33.54
+	Hs
		522938 SRC_HUMAN (20-507): 0: 586: 55.00		RHG01_HUMAN (250-412): 3.19e-19: 93.6: 32.73
+	Hs
		64642 FYN_HUMAN (30-507): 0: 586: 59.01		RHG32_HUMAN (250-462): 7.37e-18: 91.3: 29.41
+	Hs
		64648 SRC_HUMAN (20-507): 0: 586: 55.00		RHG32_HUMAN (250-462): 7.37e-18: 91.3: 29.41
+	Hs
		64643 LYN_HUMAN (1-509): 0: 582: 62.72		RHG32_HUMAN (250-462): 7.37e-18: 91.3: 29.41
+	Hs
		506538 FRK_HUMAN (50-503): 0: 530: 48.20		BCR_HUMAN (250-408): 2.36e-16: 86.3: 33.54
+	Hs
		337325 ABL1_HUMAN (49-502): 8.1e-171: 513: 42.21		BCR_HUMAN (250-408): 2.36e-16: 86.3: 33.54