Protein: DHTK1
2-oxoadipate dehydrogenase complex component E1 (E1a) (OADC-E1) (OADH-E1) (EC 1.2.4.-) (2-oxoadipate dehydrogenase, mitochondrial) (Alpha-ketoadipate dehydrogenase) (Alpha-KADH-E1) (Dehydrogenase E1 and transketolase domain-containing protein 1) (Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial)

Gene: DHTK1, DHTKD1
Organism: Homo sapiens
Interactions: 54
UniProt ID: Q96HY7

Gene Ontology (top 5):
GO:0002244 - hematopoietic progenitor cell differentiation
GO:0004591 - oxoglutarate dehydrogenase (succinyl-transferring) activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006091 - generation of precursor metabolites and energy

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

471186

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

13

High-throughput

0.618

High

1242610

FAHD1
Oxaloacetate tautomerase FAHD1, mitochondrial

2

1

High-throughput

0.611

High

279864

CISY
Citrate synthase, mitochondrial

2

4

High-throughput

0.584

High

1162487

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

2

High-throughput

0.584

High

1361501

BMAL2
Basic helix-loop-helix ARNT-like protein 2

2

2

High-throughput

0.574

High

132758

BMAL1
Basic helix-loop-helix ARNT-like protein 1

2

1

High-throughput

0.553

High

1140691

KIF14
Kinesin-like protein KIF14

1

3

High-throughput

0.553

High

225211

GATC
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial

1

0

High-throughput

0.513

High

946517

YBEY
Endoribonuclease YbeY

1

0

High-throughput

0.513

High

427926

ICAM1
Intercellular adhesion molecule 1

1

1

High-throughput

0.489

High

885010

DGKG
Diacylglycerol kinase gamma

1

1

High-throughput

0.489

High

61587

VWA8
von Willebrand factor A domain-containing protein 8

1

4

High-throughput

0.479

High

282045

MPPB
Mitochondrial-processing peptidase subunit beta

1

11

High-throughput

0.479

High

350957

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

2

High-throughput

0.479

High

412437

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.479

High

484617

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

9

High-throughput

0.479

High

519196

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

1

High-throughput

0.479

High

532871

CH60
60 kDa heat shock protein, mitochondrial

1

8

High-throughput

0.479

High

828899

MDHM
Malate dehydrogenase, mitochondrial

1

7

High-throughput

0.479

High

851992

EFTS
Elongation factor Ts, mitochondrial

1

3

High-throughput

0.479

High

1048642

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

3

High-throughput

0.479

High

1058211

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

2

High-throughput

0.479

High

1083706

MPPA
Mitochondrial-processing peptidase subunit alpha

1

12

High-throughput

0.479

High

1090499

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

5

High-throughput

0.479

High

1117807

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

9

High-throughput

0.479

High

1142629

PDK1
[Pyruvate dehydrogenase

1

8

High-throughput

0.479

High

1207103

SYAM
Alanine--tRNA ligase, mitochondrial

1

3

High-throughput

0.479

High

1234489

MRM1
rRNA methyltransferase 1, mitochondrial

1

2

High-throughput

0.479

High

1367018

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

1388238

RRFM
Ribosome-recycling factor, mitochondrial

1

2

High-throughput

0.479

High

1393895

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.479

High

1393896

TR61B
tRNA

1

2

High-throughput

0.479

High

1393897

RT26
Small ribosomal subunit protein mS26

1

2

High-throughput

0.479

High

1393898

MTG2
Mitochondrial ribosome-associated GTPase 2

1

6

High-throughput

0.479

High

1393899

MET17
Ribosome assembly protein METTL17, mitochondrial

1

2

High-throughput

0.479

High

1393900

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

6

High-throughput

0.479

High

1393902

MRES1
Mitochondrial transcription rescue factor 1

1

2

High-throughput

0.479

High

1393903

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

7

High-throughput

0.479

High

1393906

RM11
Large ribosomal subunit protein uL11m

1

2

High-throughput

0.479

High

1311238

UN45B
Protein unc-45 homolog B

1

1

High-throughput

0.470

High

593187

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.458

High

942824

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

2

High-throughput

0.437

High

1015680

RHOG
Rho-related GTP-binding protein RhoG

1

4

High-throughput

0.437

High

1255069

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

1226218

CP135
Centrosomal protein of 135 kDa

1

7

High-throughput

0.407

High

1393894

PGRP3
Peptidoglycan recognition protein 3

3

0

High-throughput

0.345

High

1312839

RIMKA
N-acetylaspartylglutamate synthase A

2

0

High-throughput

0.318

High

220709

DENR
Density-regulated protein

1

0

High-throughput

0.279

Low

1219580

MORN5
MORN repeat-containing protein 5

1

0

High-throughput

0.279

Low

1393904

IPO11
Importin-11

1

0

High-throughput

0.279

Low

1324043

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.249

Low

1393905

XPO7
Exportin-7

1

0

High-throughput

0.249

Low

1393893

C170L
Cep170-like protein

1

0

High-throughput

0.232

Low

1393901

S22AB
Solute carrier family 22 member 11

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025