HitPredict

Interactor 1: CDC7 (P06243)
Cell division control protein 7 (EC 2.7.11.1)
Gene: CDC7

Interactor 2: RPN2 (P32565)
26S proteasome regulatory subunit RPN2
Gene: RPN2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	19013276
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	HEAT_2~Pkinase
Common GO terms	GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 507 Sc			1 945
+	At
		221380 CDKA1_ARATH (276-339): 3.17e-13: 72.2: 32.81		PSD1A_ARATH (3-945): 0: 1140: 37.03
+	Sc
		565500 PHO85_YEAST (236-471): 6.83e-15: 77.2: 17.80		RPN2_YEAST (1-945): 0: 1119: 100.00
+	Sc
		339520 CDK1_YEAST (236-339): 3.85e-12: 69.1: 24.04		RPN2_YEAST (1-945): 0: 1119: 100.00
+	Hs
		568648 KAPCA_HUMAN (3-365): 7.42e-106: 321: 11.92		PSMD2_HUMAN (9-770): 0: 760: 17.31
+	Hs
		625404 CDK2_HUMAN (31-324): 4.65e-62: 206: 20.59		PSMD2_HUMAN (9-770): 0: 760: 17.31
+	Dm
		1374999 PDPK1_DROME (31-497): 4.12e-71: 243: 18.24		Q9VW54_DROME (13-770): 0: 651: 17.61
+	Sc
		412552 CDC7_YEAST (1-507): 1.6e-129: 387: 100.00		RPN1_YEAST (9-573): 1.13e-134: 430: 17.33
+	At
		621727 CDKA1_ARATH (276-339): 3.17e-13: 72.2: 32.81		PSD2A_ARATH (9-770): 0: 669: 17.76
+	Dm
		1213423 AKT1_DROME (202-440): 1.16e-17: 88.1: 10.88		Q9VW54_DROME (13-770): 0: 651: 17.61
+	At
		621667 CDKA1_ARATH (276-339): 3.17e-13: 72.2: 32.81		PSD2B_ARATH (9-770): 0: 662: 18.32
+	Sc
		339613 CDK1_YEAST (236-339): 3.85e-12: 69.1: 24.04		RPN1_YEAST (9-573): 1.13e-134: 430: 17.33