HitPredict

Interactor 1: CPNS1 (P04632)
Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit)
Gene: CAPNS1

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36964131
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008284 - positive regulation of cell population proliferation GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 268 Hs			1 768
+	Hs
		457086 CAN1_HUMAN (65-268): 3.14e-57: 196: 44.88		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1114547 PEF1_HUMAN (45-265): 1.4e-54: 179: 22.91		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		276464 PDCD6_HUMAN (103-265): 8.84e-55: 177: 27.27		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		605999 CAN2_HUMAN (65-263): 2.89e-50: 177: 43.72		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113403 CAN13_HUMAN (79-268): 6.99e-50: 175: 30.77		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		276462 PDCD6_HUMAN (103-265): 8.84e-55: 177: 27.27		CUL1_HUMAN (18-768): 0: 709: 30.57
+	Hs
		276463 PDCD6_HUMAN (103-265): 8.84e-55: 177: 27.27		CUL2_HUMAN (30-768): 0: 673: 26.17
+	Hs
		276501 PDCD6_HUMAN (103-265): 8.84e-55: 177: 27.27		CUL5_HUMAN (25-768): 0: 597: 23.77