HitPredict - High confidence protein-protein interactions

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30894540
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0001701 - in utero embryonic development GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 20 others more... GO:0005667 - transcription regulator complex GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol GO:0007405 - neuroblast proliferation GO:0008285 - negative regulation of cell population proliferation GO:0010628 - positive regulation of gene expression GO:0019899 - enzyme binding GO:0031625 - ubiquitin protein ligase binding GO:0032991 - protein-containing complex GO:0033077 - T cell differentiation in thymus GO:0043065 - positive regulation of apoptotic process GO:0043066 - negative regulation of apoptotic process GO:0043525 - positive regulation of neuron apoptotic process GO:0045892 - negative regulation of DNA-templated transcription GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding GO:0072089 - stem cell proliferation GO:0097718 - disordered domain specific binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	393
Hs

1	781

Service provided by Combinatics, Japan

Last updated: 11Aug2025