HitPredict

Interactor 1: GELS (P06396)
Gelsolin (AGEL) (Actin-depolymerizing factor) (ADF) (Brevin)
Gene: GSN

Interactor 2: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.670

Property	Details
Experiments	12941811, 15604093, 19574450
Identification Methods	pull down, two hybrid, t7 phage display
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0010628 - positive regulation of gene expression
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 782 Hs			1 920
+	Hs
		368817 GELS_HUMAN (1-782): 0: 1207: 100.00		ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20
+	Hs
		414017 GELS_HUMAN (1-782): 0: 1207: 100.00		ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51
+	Hs
		1270065 SCIN_HUMAN (51-768): 0: 1007: 59.72		ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51
+	Hs
		487386 FLII_HUMAN (373-765): 2.36e-57: 214: 22.88		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		313734 SVIL_HUMAN (551-779): 2.11e-24: 112: 21.86		ANDR_HUMAN (1-920): 0: 966: 100.00
+	Hs
		369509 FLII_HUMAN (373-765): 2.36e-57: 214: 22.88		ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20
+	Hs
		377027 VILI_HUMAN (68-467): 1.52e-69: 246: 28.22		GCR_HUMAN (444-920): 1.2e-117: 378: 40.85
+	Hs
		1023211 FLII_HUMAN (373-765): 2.36e-57: 214: 22.88		ESR2_HUMAN (435-912): 2.48e-116: 367: 21.51
+	Hs
		313719 SVIL_HUMAN (551-779): 2.11e-24: 112: 21.86		ESR1_HUMAN (378-904): 7.6e-136: 420: 22.20
+	Hs
		313722 SVIL_HUMAN (551-779): 2.11e-24: 112: 21.86		GCR_HUMAN (444-920): 1.2e-117: 378: 40.85