Interactor 1: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1

Interactor 2: TFDP2 (Q14188)
Transcription factor Dp-2 (E2F dimerization partner 2)
Gene: TFDP2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.949

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 7739537, 34591612, 16360038
Identification Methods affinity chromatography technology, coimmunoprecipitation, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DP~Rb_C
Common GO terms GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0045892 - negative regulation of DNA-templated transcription
and 2 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 928
Hs

1 446
+ Hs
+ Hs
+ Dm
+ Hs
+ At
+ Hs
+ At
+ Hs
+ Hs
+ Dm
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024