Interactor 1: CDK1 (P06493)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1

Interactor 2: KAP2 (P13861)
cAMP-dependent protein kinase type II-alpha regulatory subunit
Gene: PRKAR2A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.857

The method score is based on:

Property Details
Experiments 1918018, 9852131, 32707033
Identification Methods pull down, enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~cNMP_binding, Pkinase~RIIa
Common GO terms GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0016020 - membrane
GO:0070062 - extracellular exosome
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 297
Hs

1 404
+ Sc
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024