Interactor 1: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1

Interactor 2: AATF (Q9NY61)
Protein AATF (Apoptosis-antagonizing transcription factor) (Rb-binding protein Che-1)
Gene: AATF

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.643

The method score is based on:

Property Details
Experiments 12450794, 10783144
Identification Methods two hybrid, affinity chromatography technology, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0007346 - regulation of mitotic cell cycle
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:2001234 - negative regulation of apoptotic signaling pathway
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 928
Hs

1 560
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024