HitPredict

Interactor 1: CDK1 (P06493)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1

Interactor 2: CDKN3 (Q16667)
Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.16) (EC 3.1.3.48) (CDK2-associated dual-specificity phosphatase) (Cyclin-dependent kinase interactor 1) (Cyclin-dependent kinase-interacting protein 2) (Kinase-associated phosphatase)
Gene: CDKN3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.927

Property	Details
Experiments	26186194, 8127873, 28675297, 8242750, 24218572
Identification Methods	affinity chromatography technology, two hybrid, genetic interference, lexa b52 complementation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	CDKN3~Pkinase
Common GO terms	GO:0000082 - G1/S transition of mitotic cell cycle GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 297 Hs			1 212
+	Hs
		625470 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		CDKN3_HUMAN (1-212): 9.09e-165: 454: 100.00
+	Hs
		960097 CDK3_HUMAN (1-289): 1.71e-144: 410: 66.78		CDKN3_HUMAN (1-212): 9.09e-165: 454: 100.00