Interactor 1: CO2 (P06681)
Complement C2 (EC 3.4.21.43) (C3/C5 convertase) [Cleaved into: Complement C2b fragment; Complement C2a fragment]
Gene: C2

Interactor 2: DAF (P08174)
Complement decay-accelerating factor (CD antigen CD55)
Gene: CD55

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Sushi~Sushi, Sushi~Trypsin, Sushi~VWA
Common GO terms GO:0005576 - extracellular region
GO:0006958 - complement activation, classical pathway
GO:0045087 - innate immune response
GO:0070062 - extracellular exosome
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 752
Hs

1 381
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Last updated: 15 Jul 2024