HitPredict

Interactor 1: SIR3 (P06701)
Regulatory protein SIR3 (Silent information regulator 3)
Gene: SIR3

Interactor 2: SIR1 (P21691)
Regulatory protein SIR1 (Heterochromatin protein SIR1) (Silent information regulator 1)
Gene: SIR1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.860

Property	Details
Experiments	11805837, 28188183, 19029247
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, two hybrid, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	BAH~Sir1
Common GO terms	GO:0003682 - chromatin binding GO:0005677 - chromatin silencing complex GO:0030466 - silent mating-type cassette heterochromatin formation GO:0031507 - heterochromatin formation
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 978 Sc			1 654
+	Sc
		600276 ORC1_YEAST (1-975): 0: 754: 23.77		SIR1_YEAST (1-654): 0: 1360: 100.00