HitPredict

Interactor 1: S10A9 (P06702)
Protein S100-A9 (Calgranulin-B) (Calprotectin L1H subunit) (Leukocyte L1 complex heavy chain) (Migration inhibitory factor-related protein 14) (MRP-14) (p14) (S100 calcium-binding protein A9)
Gene: S100A9

Interactor 2: ERCC3 (P19447)
General transcription and DNA repair factor IIH helicase/translocase subunit XPB (TFIIH subunit XPB) (EC 5.6.2.4) (Basic transcription factor 2 89 kDa subunit) (BTF2 p89) (DNA 3'-5' helicase/translocase XPB) (DNA excision repair protein ERCC-3) (DNA repair protein complementing XP-B cells) (TFIIH basal transcription factor complex 89 kDa subunit) (TFIIH 89 kDa subunit) (TFIIH p89) (Xeroderma pigmentosum group B-complementing protein)
Gene: ERCC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006915 - apoptotic process
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 114 Hs			1 782
+	Hs
		584643 CRNN_HUMAN (5-108): 1.1e-33: 123: 25.96		ERCC3_HUMAN (1-782): 0: 728: 100.00
+	Hs
		584547 S100P_HUMAN (5-97): 2.82e-35: 118: 36.56		ERCC3_HUMAN (1-782): 0: 728: 100.00
+	Hs
		584551 S10A2_HUMAN (1-101): 2.02e-32: 110: 32.67		ERCC3_HUMAN (1-782): 0: 728: 100.00
+	Hs
		396680 S10A8_HUMAN (5-100): 3.01e-29: 102: 25.00		ERCC3_HUMAN (1-782): 0: 728: 100.00
+	Hs
		584618 S1A7A_HUMAN (6-105): 2.16e-26: 95.8: 24.75		ERCC3_HUMAN (1-782): 0: 728: 100.00
+	Hs
		584538 FILA_HUMAN (5-107): 2e-23: 95.4: 34.62		ERCC3_HUMAN (1-782): 0: 728: 100.00
+	Hs
		584557 S10A7_HUMAN (6-105): 8.64e-26: 94.2: 24.75		ERCC3_HUMAN (1-782): 0: 728: 100.00
+	Hs
		133841 S10A9_HUMAN (1-114): 4.07e-47: 148: 100.00		DDX3X_HUMAN (204-677): 1.56e-104: 337: 11.22
+	Hs
		134113 HORN_HUMAN (5-97): 3.47e-32: 120: 29.03		DDX3X_HUMAN (204-677): 1.56e-104: 337: 11.22
+	Hs
		134073 FILA2_HUMAN (5-106): 5.21e-28: 108: 30.91		DDX3X_HUMAN (204-677): 1.56e-104: 337: 11.22
+	Hs
		133879 FILA_HUMAN (5-107): 2e-23: 95.4: 34.62		DDX3X_HUMAN (204-677): 1.56e-104: 337: 11.22