HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: H2B1C (P62807)
Histone H2B type 1-C/E/F/G/I (Histone H2B.1 A) (Histone H2B.a) (H2B/a) (Histone H2B.g) (H2B/g) (Histone H2B.h) (H2B/h) (Histone H2B.k) (H2B/k) (Histone H2B.l) (H2B/l)
Gene: H2BC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006334 - nucleosome assembly
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 126
+	Hs
		418323 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		H2B2E_HUMAN (1-126): 5.61e-54: 166: 99.21
+	Hs
		417977 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		H2B1B_HUMAN (1-126): 1.52e-53: 165: 97.62
+	Hs
		418359 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		H2B2C_HUMAN (1-96): 1.13e-43: 143: 90.63
+	Hs
		271297 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		H2B1C_HUMAN (1-126): 1.05e-53: 166: 100.00