HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: SKI2 (Q15477)
Superkiller complex protein 2 (Ski2) (EC 3.6.4.13) (Helicase-like protein) (HLP)
Gene: SKIC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26496610, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 1246
+	Hs
		418704 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		DDX21_HUMAN (160-967): 3.81e-102: 344: 13.55
+	Hs
		133844 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		DDX3X_HUMAN (114-621): 1.37e-95: 322: 10.44
+	Hs
		418453 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		ASCC3_HUMAN (177-1036): 2.58e-64: 243: 15.46
+	Hs
		271427 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		DDX21_HUMAN (160-967): 3.81e-102: 344: 13.55
+	Hs
		271361 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		ASCC3_HUMAN (177-1036): 2.58e-64: 243: 15.46