Protein: ATLA2
Atlastin-2 (ATL-2) (EC 3.6.5.-) (ADP-ribosylation factor-like protein 6-interacting protein 2)

Gene: ATLA2, ATL2
Organism: Homo sapiens
Interactions: 172
UniProt ID: Q8NHH9

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0007029 - endoplasmic reticulum organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1231441

ATLA3
Atlastin-3

2

15

High-throughput

0.811

High

990522

1433Z
14-3-3 protein zeta/delta

2

4

High-throughput

0.705

High

730071

1433B
14-3-3 protein beta/alpha

1

4

High-throughput

0.691

High

1340128

COPG1
Coatomer subunit gamma-1

3

7

High-throughput

0.675

High

1027096

REEP5
Receptor expression-enhancing protein 5

3

4

High-throughput

0.650

High

158266

COPE
Coatomer subunit epsilon

2

3

High-throughput

0.628

High

630174

ACM3
Muscarinic acetylcholine receptor M3

2

1

High-throughput

0.628

High

1340079

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

2

2

High-throughput

0.628

High

1291844

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

3

14

High-throughput

0.609

High

1056865

FMR1
Fragile X messenger ribonucleoprotein 1

2

1

High-throughput

0.584

High

104354

F5H6I7
Atlastin GTPase 3

1

14

High-throughput

0.575

High

1340083

ATLA1
Atlastin-1

1

16

High-throughput

0.575

High

406909

MAS
Proto-oncogene Mas

2

18

High-throughput

0.574

High

1196205

S22A6
Solute carrier family 22 member 6

2

4

High-throughput

0.574

High

1340117

C5AR2
C5a anaphylatoxin chemotactic receptor 2

2

17

High-throughput

0.574

High

904016

BAP31
B-cell receptor-associated protein 31

2

3

High-throughput

0.571

High

1333908

DHB11
Estradiol 17-beta-dehydrogenase 11

2

8

High-throughput

0.571

High

851074

LPAR6
Lysophosphatidic acid receptor 6

2

13

High-throughput

0.558

High

1031464

IFM3
Interferon-induced transmembrane protein 3

2

1

High-throughput

0.558

High

167167

T4S5
Transmembrane 4 L6 family member 5

1

2

High-throughput

0.536

High

182677

GP182
G-protein coupled receptor 182

1

17

High-throughput

0.536

High

297232

PRAF3
PRA1 family protein 3

1

1

High-throughput

0.536

High

638476

FPR1
fMet-Leu-Phe receptor

1

13

High-throughput

0.536

High

669033

FPR2
N-formyl peptide receptor 2

1

13

High-throughput

0.536

High

719815

V2R
Vasopressin V2 receptor

1

6

High-throughput

0.536

High

773575

COPB2
Coatomer subunit beta'

1

7

High-throughput

0.536

High

854554

S15A1
Solute carrier family 15 member 1

1

1

High-throughput

0.536

High

867991

GLR
Glucagon receptor

1

3

High-throughput

0.536

High

921964

COPA
Coatomer subunit alpha

1

7

High-throughput

0.536

High

964037

COPZ1
Coatomer subunit zeta-1

1

3

High-throughput

0.536

High

1006922

KC1G2
Casein kinase I isoform gamma-2

1

4

High-throughput

0.536

High

1139228

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

3

High-throughput

0.536

High

1212749

ZFY27
Protrudin

1

2

Small-scale

0.536

High

1325872

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

1

High-throughput

0.536

High

1340090

CML1
Chemerin-like receptor 1

1

13

High-throughput

0.536

High

1340094

ESYT1
Extended synaptotagmin-1

1

7

High-throughput

0.536

High

1340107

RTN4
Reticulon-4

1

11

High-throughput

0.536

High

1340118

COPG2
Coatomer subunit gamma-2

1

7

High-throughput

0.536

High

1340123

SC6A5
Sodium- and chloride-dependent glycine transporter 2

1

1

High-throughput

0.536

High

673780

LAMA1
Laminin subunit alpha-1

1

0

High-throughput

0.513

High

903422

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

0

High-throughput

0.513

High

1104741

NNTM
NAD(P) transhydrogenase, mitochondrial

1

0

High-throughput

0.513

High

1185815

PTHD3
Patched domain-containing protein 3

1

0

High-throughput

0.513

High

1340087

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

0

High-throughput

0.513

High

1340113

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

0

High-throughput

0.513

High

133283

P2Y10
Putative P2Y purinoceptor 10

1

15

High-throughput

0.489

High

699564

IL1R2
Interleukin-1 receptor type 2

1

1

High-throughput

0.489

High

711575

NK3R
Neuromedin-K receptor

1

4

High-throughput

0.489

High

771184

APJ
Apelin receptor

1

7

High-throughput

0.489

High

774092

ADDA
Alpha-adducin

1

3

High-throughput

0.489

High

832431

OPRX
Nociceptin receptor

1

7

High-throughput

0.489

High

936089

PAR2
Proteinase-activated receptor 2

1

15

High-throughput

0.489

High

1101595

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

15

High-throughput

0.489

High

1106800

VPP3
V-type proton ATPase 116 kDa subunit a 3

1

1

High-throughput

0.489

High

1156940

CNGA3
Cyclic nucleotide-gated channel alpha-3

1

1

High-throughput

0.489

High

1329461

KTAP2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2

1

1

High-throughput

0.489

High

1340104

NELFA
Negative elongation factor A

1

1

High-throughput

0.489

High

1340114

RGL1
Ral guanine nucleotide dissociation stimulator-like 1

1

1

High-throughput

0.489

High

1340119

HCST
Hematopoietic cell signal transducer

1

1

High-throughput

0.489

High

1340120

STK39
STE20/SPS1-related proline-alanine-rich protein kinase

1

1

High-throughput

0.489

High

1340122

KLDC2
Kelch domain-containing protein 2

1

1

High-throughput

0.489

High

1340126

GPR45
Probable G-protein coupled receptor 45

1

8

High-throughput

0.489

High

1340099

ARL6
ADP-ribosylation factor-like protein 6

1

5

Small-scale

0.481

High

174003

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

1

High-throughput

0.479

High

418286

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

3

High-throughput

0.479

High

537553

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

942762

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.479

High

962288

RHOA
Transforming protein RhoA

1

2

High-throughput

0.479

High

1287383

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

3

Small-scale

0.479

High

1340096

DERL1
Derlin-1

1

1

High-throughput

0.479

High

1340101

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

4

High-throughput

0.479

High

922748

CCHL
Holocytochrome c-type synthase

1

0

High-throughput

0.458

High

963527

B2MG
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]

1

0

High-throughput

0.458

High

1309853

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.458

High

185870

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.457

High

48708

ESYT2
Extended synaptotagmin-2

1

7

High-throughput

0.445

High

50628

HACL2
2-hydroxyacyl-CoA lyase 2

1

2

High-throughput

0.445

High

60380

NBAS
NBAS subunit of NRZ tethering complex

1

2

High-throughput

0.445

High

211825

ZW10
Centromere/kinetochore protein zw10 homolog

1

2

High-throughput

0.445

High

215609

EMC8
ER membrane protein complex subunit 8

1

2

High-throughput

0.445

High

275539

RTN2
Reticulon-2

1

11

High-throughput

0.445

High

283314

ERLN1
Erlin-1

1

2

High-throughput

0.445

High

328958

RTN3
Reticulon-3

1

11

High-throughput

0.445

High

333108

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

7

High-throughput

0.445

High

360046

NB5R3
NADH-cytochrome b5 reductase 3

1

2

High-throughput

0.445

High

462525

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

2

High-throughput

0.445

High

535313

BIP
Endoplasmic reticulum chaperone BiP

1

6

High-throughput

0.445

High

564094

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.445

High

567036

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

2

High-throughput

0.445

High

697963

CALR
Calreticulin

1

5

High-throughput

0.445

High

698917

CALX
Calnexin

1

5

High-throughput

0.445

High

873274

COPD
Coatomer subunit delta

1

3

High-throughput

0.445

High

876939

KC1A
Casein kinase I isoform alpha

1

3

High-throughput

0.445

High

888929

TMEDA
Transmembrane emp24 domain-containing protein 10

1

8

High-throughput

0.445

High

903741

SSRD
Translocon-associated protein subunit delta

1

2

High-throughput

0.445

High

921725

COPB
Coatomer subunit beta

1

2

High-throughput

0.445

High

987126

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

2

High-throughput

0.445

High

1009860

NUCB2
Nucleobindin-2

1

2

High-throughput

0.445

High

1015068

ARF5
ADP-ribosylation factor 5

1

3

High-throughput

0.445

High

1097010

PRDX4
Peroxiredoxin-4

1

2

High-throughput

0.445

High

1131327

GANAB
Neutral alpha-glucosidase AB

1

2

High-throughput

0.445

High

1136283

EMC2
ER membrane protein complex subunit 2

1

4

High-throughput

0.445

High

1139349

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

2

High-throughput

0.445

High

1145627

RCN1
Reticulocalbin-1

1

2

High-throughput

0.445

High

1146585

TMED2
Transmembrane emp24 domain-containing protein 2

1

8

High-throughput

0.445

High

1147801

DHC24
Delta(24)-sterol reductase

1

2

High-throughput

0.445

High

1152824

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

4

High-throughput

0.445

High

1199219

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

8

High-throughput

0.445

High

1248633

LCLT1
Lysocardiolipin acyltransferase 1

1

3

High-throughput

0.445

High

1316261

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

5

High-throughput

0.445

High

1327899

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

2

High-throughput

0.445

High

1330318

EMC1
ER membrane protein complex subunit 1

1

2

High-throughput

0.445

High

1337602

PDZD8
PDZ domain-containing protein 8

1

2

High-throughput

0.445

High

1340077

MCFD2
Multiple coagulation factor deficiency protein 2

1

2

High-throughput

0.445

High

1340082

SCFD1
Sec1 family domain-containing protein 1

1

2

High-throughput

0.445

High

1340084

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

2

High-throughput

0.445

High

1340085

S67A1
Solute carrier family 67 member A1

1

2

High-throughput

0.445

High

1340086

ASTRA
Protein Aster-A

1

2

High-throughput

0.445

High

1340088

SCYL1
N-terminal kinase-like protein

1

5

High-throughput

0.445

High

1340093

ERP44
Endoplasmic reticulum resident protein 44

1

3

High-throughput

0.445

High

1340095

NDC1
Nucleoporin NDC1

1

2

High-throughput

0.445

High

1340097

WDR11
WD repeat-containing protein 11

1

2

High-throughput

0.445

High

1340098

LNP
Endoplasmic reticulum junction formation protein lunapark

1

2

High-throughput

0.445

High

1340102

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

2

High-throughput

0.445

High

1340103

TMX1
Thioredoxin-related transmembrane protein 1

1

6

High-throughput

0.445

High

1340106

APMAP
Adipocyte plasma membrane-associated protein

1

2

High-throughput

0.445

High

1340108

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

2

High-throughput

0.445

High

1340109

TM38B
Trimeric intracellular cation channel type B

1

2

High-throughput

0.445

High

1340112

TECR
Very-long-chain enoyl-CoA reductase

1

2

High-throughput

0.445

High

1340115

VAPA
Vesicle-associated membrane protein-associated protein A

1

7

High-throughput

0.445

High

1340121

S27A6
Long-chain fatty acid transport protein 6

1

1

High-throughput

0.445

High

1340124

DHRS7
Dehydrogenase/reductase SDR family member 7

1

5

High-throughput

0.445

High

1340125

TMED5
Transmembrane emp24 domain-containing protein 5

1

8

High-throughput

0.445

High

372629

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

412284

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.437

High

1004859

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.437

High

1107036

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.437

High

1229573

VIR
Protein virilizer homolog

1

1

High-throughput

0.437

High

1254730

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

1337286

ACRBP
Acrosin-binding protein

1

1

High-throughput

0.437

High

1340105

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

1340116

NYAP2
Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2

1

1

High-throughput

0.437

High

841218

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.426

High

104292

F5H5S8
Acrosin-binding protein

1

1

High-throughput

0.407

High

213630

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

2

High-throughput

0.407

High

296531

STAM2
Signal transducing adapter molecule 2

1

2

High-throughput

0.407

High

319003

MICA2
[F-actin]-monooxygenase MICAL2

1

3

High-throughput

0.407

High

883120

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

3

High-throughput

0.407

High

1258782

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

2

High-throughput

0.407

High

1338197

VP37A
Vacuolar protein sorting-associated protein 37A

1

2

High-throughput

0.407

High

1340089

NUDC1
NudC domain-containing protein 1

1

2

High-throughput

0.407

High

1340092

PXL2A
Peroxiredoxin-like 2A

1

2

High-throughput

0.407

High

1340100

RGAP1
Rac GTPase-activating protein 1

1

3

High-throughput

0.407

High

1340110

GPTC2
G patch domain-containing protein 2

1

2

High-throughput

0.407

High

1340111

PSD3
PH and SEC7 domain-containing protein 3

1

2

High-throughput

0.407

High

1340127

SERC
Phosphoserine aminotransferase

1

2

High-throughput

0.407

High

130550

SPT5H
Transcription elongation factor SPT5

1

0

High-throughput

0.279

Low

296065

IDHC
Isocitrate dehydrogenase [NADP] cytoplasmic

1

0

High-throughput

0.279

Low

596762

DPEP1
Dipeptidase 1

1

0

High-throughput

0.279

Low

821745

CD79B
B-cell antigen receptor complex-associated protein beta chain

1

0

High-throughput

0.279

Low

1005751

RPP38
Ribonuclease P protein subunit p38

1

0

High-throughput

0.279

Low

1013492

LSM11
U7 snRNA-associated Sm-like protein LSm11

1

0

High-throughput

0.279

Low

1055130

CCG1
Voltage-dependent calcium channel gamma-1 subunit

1

0

High-throughput

0.279

Low

1310249

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

1340080

DEN1A
DENN domain-containing protein 1A

1

0

High-throughput

0.279

Low

1340081

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.279

Low

1340091

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

0

High-throughput

0.279

Low

1340078

S7A13
Solute carrier family 7 member 13

1

0

High-throughput

0.269

Low

589209

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

695992

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

768691

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1150397

NCOA2
Nuclear receptor coactivator 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025