HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: SENP5 (Q96HI0)
Sentrin-specific protease 5 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP5)
Gene: SENP5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	33961781, 26186194, 28514442, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 755
+	Hs
		271384 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		SENP5_HUMAN (1-755): 0: 1139: 100.00
+	Hs
		418661 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		SENP3_HUMAN (420-753): 7.1e-90: 295: 45.51
+	Hs
		271411 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		SENP3_HUMAN (420-753): 7.1e-90: 295: 45.51