HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: TRIP6 (Q15654)
Thyroid receptor-interacting protein 6 (TR-interacting protein 6) (TRIP-6) (Opa-interacting protein 1) (OIP-1) (Zyxin-related protein 1) (ZRP-1)
Gene: TRIP6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	25416956
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001725 - stress fiber GO:0005829 - cytosol GO:0005856 - cytoskeleton
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 476
+	Hs
		1076422 Q5VU62_HUMAN (128-285): 1.66e-39: 137: 100.00		TRIP6_HUMAN (1-476): 4.58e-97: 302: 100.00
+	Hs
		932007 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		TRIP6_HUMAN (1-476): 4.58e-97: 302: 100.00
+	Hs
		451325 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		TES_HUMAN (141-457): 1.24e-56: 195: 19.09
+	Hs
		419055 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77
+	Hs
		451318 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77
+	Hs
		434438 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77
+	Hs
		932058 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77
+	Mm
		886037 TPM1_MOUSE (2-285): 2.33e-44: 153: 91.55		PDLI5_MOUSE (62-334): 6.71e-10: 63.5: 11.03
+	Mm
		886046 TPM2_MOUSE (2-285): 1.89e-39: 140: 86.62		PDLI5_MOUSE (62-334): 6.71e-10: 63.5: 11.03
+	Hs
		434422 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		PDLI5_HUMAN (249-334): 7.45e-09: 60: 20.93
+	Hs
		1080683 FKB15_HUMAN (1-284): 5.16e-27: 112: 13.40		ZYX_HUMAN (91-467): 2.51e-15: 80.4: 18.02
+	Hs
		110806 H7BYY1_HUMAN (2-228): 1.39e-10: 62.2: 21.37		PDLI7_HUMAN (111-473): 4.43e-25: 109: 13.77