HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: CEP63 (Q96MT8)
Centrosomal protein of 63 kDa (Cep63)
Gene: CEP63

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35709258
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 703
+	Hs
		932041 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		CEP63_HUMAN (1-703): 1.84e-64: 228: 100.00
+	Dm
		419108 TPM1_DROME (2-282): 8.67e-51: 171: 45.97		MYSN_DROME (1-430): 3.81e-15: 82.1: 12.70
+	Hs
		418895 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		451201 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		434354 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		148289 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		419011 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Hs
		451293 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Hs
		418974 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		CROCC_HUMAN (102-701): 1.82e-12: 73.2: 9.08
+	Hs
		451267 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		CROCC_HUMAN (102-701): 1.82e-12: 73.2: 9.08
+	Hs
		724765 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		434415 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Hs
		148661 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Dm
		404216 TPM2_DROME (2-284): 6.48e-36: 131: 47.70		MYSA_DROME (1-419): 8.7e-13: 74.2: 14.45
+	Hs
		932031 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Hs
		110796 H7BYY1_HUMAN (2-228): 1.39e-10: 62.2: 21.37		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		1268126 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Hs
		110802 H7BYY1_HUMAN (2-228): 1.39e-10: 62.2: 21.37		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Rn
		222476 MRCKB_RAT (3-285): 1.56e-12: 69.5: 14.09		MRCKA_RAT (80-483): 2.52e-09: 62.9: 16.67