Interactor 1: TOP2 (P06786)
DNA topoisomerase 2 (EC 5.6.2.2) (DNA topoisomerase II)
Gene: TOP2

Interactor 2: SIZ1 (Q04195)
E3 SUMO-protein ligase SIZ1 (EC 2.3.2.-) (E3 SUMO-protein transferase SIZ2) (SAP and Miz-finger domain-containing protein 1) (Ubiquitin-like protein ligase 1)
Gene: SIZ1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.595

The method score is based on:

Property Details
Experiments 16204216, 23712011
Identification Methods enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1428
Sc

1 904
+ Hs
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024