HitPredict

Interactor 1: A0A087WSW0 (A0A087WSW0)
Helt bHLH transcription factor
Gene: HELT

Interactor 2: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	unassigned1304
Identification Methods	validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 327 Hs			1 197
+	Hs
		62468 HELT_HUMAN (46-327): 8.41e-99: 293: 82.98		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00
+	Hs
		980671 HEY1_HUMAN (24-321): 6.8e-62: 201: 27.89		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		980604 HES1_HUMAN (25-296): 3.55e-49: 167: 17.45		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		980948 HES6_HUMAN (32-296): 1.1e-47: 161: 19.26		TLE4_HUMAN (2-191): 3.57e-112: 338: 68.59
+	Hs
		980638 HES6_HUMAN (32-296): 1.1e-47: 161: 19.26		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		980840 HES6_HUMAN (32-296): 1.1e-47: 161: 19.26		TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50
+	Mm
		1143960 HES6_MOUSE (32-296): 1.29e-49: 166: 20.37		TLE1_MOUSE (2-197): 2.15e-101: 310: 63.00
+	Hs
		980651 HES4_HUMAN (25-280): 3.44e-39: 139: 21.84		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		993550 HES6_HUMAN (32-296): 1.1e-47: 161: 19.26		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00
+	Hs
		980686 HES1_HUMAN (25-296): 3.55e-49: 167: 17.45		TLE2_HUMAN (2-149): 6.71e-80: 253: 71.62
+	Hs
		146485 BHE40_HUMAN (24-274): 8.81e-18: 85.3: 19.50		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00
+	Dm
		558377 DPN_DROME (49-325): 6.57e-46: 163: 18.42		GROU_DROME (2-163): 3.54e-59: 198: 54.44
+	Dm
		558399 Q9VJ16_DROME (30-299): 3.02e-41: 151: 18.66		GROU_DROME (2-163): 3.54e-59: 198: 54.44
+	Dm
		534341 HAIR_DROME (41-285): 8.72e-29: 115: 19.60		GROU_DROME (2-163): 3.54e-59: 198: 54.44
+	Dm
		558372 ESMD_DROME (43-216): 1.66e-20: 88.7: 20.57		GROU_DROME (2-163): 3.54e-59: 198: 54.44
+	Dm
		525718 ESM7_DROME (44-223): 5.35e-20: 88: 20.00		GROU_DROME (2-163): 3.54e-59: 198: 54.44
+	Dm
		558369 ESM3_DROME (47-296): 5.35e-19: 86: 16.60		GROU_DROME (2-163): 3.54e-59: 198: 54.44
+	Dm
		558370 ESMB_DROME (47-265): 1.34e-17: 81.4: 18.26		GROU_DROME (2-163): 3.54e-59: 198: 54.44