HitPredict

Interactor 1: NFL (P07196)
Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein)
Gene: NEFL

Interactor 2: CRBG1 (Q9Y4K1)
Beta/gamma crystallin domain-containing protein 1 (Absent in melanoma 1 protein)
Gene: CRYBG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 1723
+	Hs
		409287 K2C8_HUMAN (69-431): 4.2e-132: 394: 36.44		CRBG1_HUMAN (1-1723): 0: 1301: 100.00
+	Hs
		1081770 AINX_HUMAN (66-401): 1.66e-91: 290: 58.11		CRBG1_HUMAN (1-1723): 0: 1301: 100.00
+	Hs
		443901 VIME_HUMAN (34-402): 6.74e-84: 270: 49.59		CRBG1_HUMAN (1-1723): 0: 1301: 100.00
+	Hs
		422474 NFM_HUMAN (82-409): 4.21e-72: 249: 54.71		CRBG1_HUMAN (1-1723): 0: 1301: 100.00
+	Hs
		409114 K2C8_HUMAN (69-431): 4.2e-132: 394: 36.44		CRBG3_HUMAN (500-1721): 0: 810: 26.89
+	Hs
		422166 NFL_HUMAN (1-543): 1.42e-151: 446: 100.00		ANK2_HUMAN (2-978): 1.16e-37: 158: 14.20
+	Hs
		422136 NFL_HUMAN (1-543): 1.42e-151: 446: 100.00		NFH_HUMAN (274-669): 2.16e-11: 71.4: 16.63
+	Rn
		562617 NFL_RAT (1-543): 3.78e-148: 438: 94.67		NFH_RAT (204-678): 5.25e-09: 63.3: 16.21
+	Hs
		409180 K2C8_HUMAN (69-431): 4.2e-132: 394: 36.44		TITIN_HUMAN (408-988): 1.94e-10: 68.6: 6.75
+	Hs
		965108 AINX_HUMAN (66-401): 1.66e-91: 290: 58.11		ANK2_HUMAN (2-978): 1.16e-37: 158: 14.20
+	Hs
		443464 VIME_HUMAN (34-402): 6.74e-84: 270: 49.59		ANK2_HUMAN (2-978): 1.16e-37: 158: 14.20
+	Hs
		422380 NFM_HUMAN (82-409): 4.21e-72: 249: 54.71		ANK2_HUMAN (2-978): 1.16e-37: 158: 14.20
+	Hs
		781878 PERI_HUMAN (9-401): 1.77e-69: 232: 48.12		ANK2_HUMAN (2-978): 1.16e-37: 158: 14.20
+	Hs
		517802 AINX_HUMAN (66-401): 1.66e-91: 290: 58.11		NFH_HUMAN (274-669): 2.16e-11: 71.4: 16.63
+	Hs
		422335 NFM_HUMAN (82-409): 4.21e-72: 249: 54.71		NFH_HUMAN (274-669): 2.16e-11: 71.4: 16.63
+	Hs
		422431 NFM_HUMAN (82-409): 4.21e-72: 249: 54.71		TITIN_HUMAN (408-988): 1.94e-10: 68.6: 6.75