HitPredict

Interactor 1: ITB2 (P05107)
Integrin beta-2 (Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD antigen CD18)
Gene: ITGB2

Interactor 2: FBX2 (Q9UK22)
F-box only protein 2
Gene: FBXO2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001540 - amyloid-beta binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 769 Hs			1 296
+	Hs
		431934 ITB1_HUMAN (5-766): 0: 702: 44.49		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		431911 ITB1_HUMAN (5-766): 0: 702: 44.49		FBX6_HUMAN (40-296): 2.42e-133: 381: 49.81
+	Hs
		612125 ITB5_HUMAN (23-760): 0: 634: 37.65		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		612122 ITB5_HUMAN (23-760): 0: 634: 37.65		FBX6_HUMAN (40-296): 2.42e-133: 381: 49.81
+	Hs
		683660 ITB8_HUMAN (14-728): 3.6e-176: 526: 32.73		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		1236161 TEN4_HUMAN (500-721): 1.38e-34: 144: 17.18		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		1449504 TEN2_HUMAN (355-562): 2.89e-27: 121: 17.94		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		1236157 TEN4_HUMAN (500-721): 1.38e-34: 144: 17.18		FBX6_HUMAN (40-296): 2.42e-133: 381: 49.81
+	Hs
		1454331 TEN3_HUMAN (356-513): 1.68e-19: 96.3: 11.11		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		673793 LAMA1_HUMAN (433-710): 7.74e-15: 81.3: 13.18		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		666734 TENA_HUMAN (574-720): 2.46e-12: 73.2: 21.19		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		857586 NOTC1_HUMAN (369-614): 7.44e-09: 61.6: 12.22		FBX2_HUMAN (1-296): 5.15e-147: 416: 100.00
+	Hs
		666731 TENA_HUMAN (574-720): 2.46e-12: 73.2: 21.19		FBX6_HUMAN (40-296): 2.42e-133: 381: 49.81